植物学报2024，Vol.59Issue(3)：481-494,14.DOI:10.11983/CBB23074
拟南芥光敏色素B氨基酸位点突变对其结构与功能的影响
Effect of Amino Acid Point Mutations on the Structure and Func-tion of Phytochrome B in Arabidopsis thaliana
摘要
Abstract
Organisms have evolved different photoreceptors to adapt to the ever-changing conditions of the external light environment.Phytochromes(phys)are one of the classic plant photoreceptors,mainly perceiving red and far-red light.Phytochromes detect red and far-red light through the light conversion between the dark-adapted Pr state and the light-activated Pfr state.All plant phytochromes have a conserved N-terminal photoreceptor region and a C-terminal regulatory region.The N-terminal includes NTE,PAS,GAF,and PHY subdomains,while C-terminal includes two PAS domains and a histidine kinase-related domain(HKRD).In order to understand how the structure of photochromes con-trols its function,many function-deficient photochrome derivatives and amino acid point mutants have been obtained and studied.The N-terminal domain plays important roles in the spectral properties,light signal perception and light signal transduction of phyB.The C-terminal domain is essential for dimerization and nuclear localization of photochrome.This paper mainly reviews point mutations of amino acid in various subdomains of phyB in Arabidopsis thaliana and their ef-fects on the function of phyB,in order to have a better understanding of the structure and functional regulation of phyB.It lays a foundation for obtaining crops with desired agronomic characteristics through gene editing.关键词
光敏色素B/拟南芥/结构域/氨基酸位点突变/功能Key words
phyB/Arabidopsis thaliana/domain/amino acid point mutation/function引用本文复制引用
陈艳晓,郑崇珂,谢先芝,李亚萍,周晋军,解丽霞,彭永彬,孙伟,和亚男,蒋聪慧,王增兰..拟南芥光敏色素B氨基酸位点突变对其结构与功能的影响[J].植物学报,2024,59(3):481-494,14.基金项目
国家自然科学基金(No.32070216)和山东省农业科学院农业科技创新工程(No.CXGC2023A15) （No.32070216）
