中国实用妇科与产科杂志2024，Vol.40Issue(6)：618-623,6.DOI:10.19538/j.fk2024060111
肥胖合并不孕症的诊治
Diagnosis and treatment of obesity with infertili-ty
摘要
Abstract
Over the past few decades,the incidence of overweight and obesity have been increasing expo-nentially and have now become a global epidemic,leading to an increase in corresponding health payment costs.The obesity rate in women is significantly higher than that in men,and the relationship between fertility and obesity is complex,involving the hypothalamic-pituitary-ovarian axis,neuroendocrine system,and adipose tissue.The exact pathophysiological mechanism by which obesity reduces fertility is still unclear and may be multifactorial,including anovulation,insulin resistance,and changes in gonadotropin.There is also controversy over whether oocyte quality or endometrial receptivity play a greater role in obese and infertile patients.Although there is currently insufficient evi-dence to suggest that maternal weight loss interventions before pregnancy or assisted reproductive therapy can improve live birth rates.But it can be clarified that weight loss intervention can reduce the risk of IVF related complications and pregnancy complications,and increase the probability of healthy pregnancy and live birth.关键词
肥胖/不孕症/诊断/治疗Key words
obesity/infertility/diagnosis/treatment分类
医药卫生引用本文复制引用
应瑛,刘见桥..肥胖合并不孕症的诊治[J].中国实用妇科与产科杂志,2024,40(6):618-623,6.基金项目
国家重点研发计划(2022YFC2702504) （2022YFC2702504）
国家自然科学基金(82371659) （82371659）
