肿瘤防治研究2024，Vol.51Issue(6)：448-454,7.DOI:10.3971/j.issn.1000-8578.2024.24.0004
基于CiteSpace及VOSviewer的乳腺癌微环境研究热点可视化分析
Visualization Analysis of Research Hotspots of Breast Cancer Microenvironment Based on CiteSpace and VOSviewer
摘要
Abstract
Objective To explore the status of knowledge graph-based research into breast cancer micro-environment and to predict future research hotspots.Methods The literature related to breast cancer microenvironment in recent 20 years was retrieved from CNKI and Web of Science Core Collection database and analyzed with CiteSpace and VOSviewer.Results A total of 825 Chinese articles and 16,221 English articles were retrieved.Visual analysis showed that research focus has gradually shifted from cellular research to molecular research and drug innovation.Cancer stem cells,PD-1,PD-L1,immune checkpoint inhibitors,and nanoparticles are the main subjects of interest in research on breast cancer microenvironment,and the United States has the largest number of studies on breast cancer microenvironment,followed by China and Italy.Conclusion Current research mainly focuses on tumor stemness,immunotherapy,and nanodeli-very.Owing to deepening research in this field,the targeting of the breast cancer microenvironment for the prevention of tumor development and metastasis and improvement of tumor prognosis has emerged as a new research direction.关键词
乳腺癌微环境/机制探索/肿瘤治疗/可视化分析/Citespace/VOSviewerKey words
Breast cancer microenvironment/Mechanism exploration/Cancer treatment/Visual analysis/Citespace/VOSviewer分类
医药卫生引用本文复制引用
方宇航,谢伊,杨舒涵,刘苏颖,房立源,王妍,王润兮,张英..基于CiteSpace及VOSviewer的乳腺癌微环境研究热点可视化分析[J].肿瘤防治研究,2024,51(6):448-454,7.基金项目
The Sub Project of the National Traditional Chinese Medicine Inheritance and Innovation Team(No.ZYYCXTD-C-C202205) （No.ZYYCXTD-C-C202205）
Director Project of China Traditional Chinese Medicine Evidence-based Medicine Center Business Laboratory(No.2020YJSZX-3) 国家中医药传承创新团队项目(ZYYCXTD-C-202205) （No.2020YJSZX-3）
中国中医药循证医学中心业务研究室主任专项(2020YJSZX-3) （2020YJSZX-3）
