中国现代中药2024，Vol.26Issue(6)：978-988,11.DOI:10.13313/j.issn.1673-4890.20231016004
蛇葡萄属药用植物亲缘学研究
Pharmacophylogenetic Relationship of Ampelopsis
摘要
Abstract
Ampelopsis Michaux is a genus of perennial woody vine encompassing roughly 30 species globally,of which approximately 17 are found in China,with the majority being endemic.Historically,most species of this genus have been revered for their medicinal properties,extensively consumed as therapeutic tea beverages across various ethnic groups.Recent taxonomical assessments,underpinned by phylogenetic relationships and morphological criteria,have led to the delineation of the species possessing pinnate compound leaves from Ampelopsis,subsequently categorizing them into a new genus termed Nekemias.Yet,corroborative evidence,particularly from phytochemical analyses,remains paramount.This study delves into the genetic affinities,chemical profiles,and pharmacological properties of Ampelopsis.Notably,while the plants of this genus are prolific in flavonoids,different species showcase distinct chemical constituents.For instance,those with pinnate compound leaves predominantly contain flavonoids such as dihydromyricetin and myricetin,whereas other species have phenolic acids like resveratrol and catechin.These chemical compounds demonstrate anti-tumor,hepatoprotective,and antimicrobial activities,resonating with traditional medicinal uses.Probing into the pharmacophylogenetic relationship of Ampelopsis helps to pave the way for conservation and therapeutic potential enhancement of plants belonging to this genus.关键词
蛇葡萄属/化学成分/传统功效/药理活性/药用植物亲缘学Key words
Ampelopsis Michaux/chemical constituents/traditional medicinal uses/pharmacological activity/pharmacophylogeny分类
医药卫生引用本文复制引用
曾铁鑫,许利嘉,宋颜君,马培,陈之端,肖培根..蛇葡萄属药用植物亲缘学研究[J].中国现代中药,2024,26(6):978-988,11.基金项目
中国医学科学院医学与健康科技创新工程项目(2021-I2M-1-031) （2021-I2M-1-031）
国家科技基础资源调查专项(2018FY100700) （2018FY100700）
广西科技基地和人才专项(AD22080012) （AD22080012）
