海南医学院学报2024，Vol.30Issue(13)：1002-1018,17.DOI:10.13210/j.cnki.jhmu.20230907.001
中药汤剂治疗成人重症肺炎疗效的网状Meta分析
Network meta-analysis of the efficacy of Chinese herbal decoction in the treatment of adult severe pneumonia
摘要
Abstract
Objective:Based on network meta-analysis,the efficacy of different Chinese herbal decoction in the treatment of adult severe pneumonia was evaluated.Methods:Computer search of CNKI,VIP,Wangfang,Cochrane Library,Embase,PubMed,Web of science databases.randomized controlled trials(RCT)on TCM decoction for severe pneumonia in adults were collected up to July 31,2023.The Cochrane bias risk assessment tool was used to assess the quality of the included literature,and Stata17.0 software was used to perform a network meta-analysis based on the frequency framework.Results:Finally,40 RCTs were included,involving 13 traditional Chinese medicines and 3 773 patients.The results of network meta-analysis showed that Maxingshigan Decoction combined with QianjinWeijian Decoction+Western medicine routine may be the most effective interven-tion in improving clinical efficacy,QingfeiTongfu Decoction+Western medicine routine may be the most effective in improving CRP,QingjinHuatan decoction+Western medicine routine may be the most effective in improving IL-6 and TNF-α.Maxingshi-gan Decoction+Western medicine routine may be the most effective in improving PCT,Xuanbai Chengqi decoction+Western medicine routine may be the most effective in improving APACHE II and CPIS.Conclusion:The curative effect of TCM decoc-tion combined with conventional western medicine on adult severe pneumonia is better than that of conventional Western medicine and the adverse reaction is less.However,limited by the quality and number of included literatures,the above conclusions still need to be further verified.关键词
中药汤剂/重症肺炎/网状Meta分析Key words
Traditional Chinese medicine decoction/Severe pneumonia/Network meta-analysis分类
医药卫生引用本文复制引用
王晓锦,李争,李风森..中药汤剂治疗成人重症肺炎疗效的网状Meta分析[J].海南医学院学报,2024,30(13):1002-1018,17.基金项目
This study was supported by Research and Development of Key Public Health Technologies and Construction of Epidemic Prevention System in Xinjiang(2020A03004) 新疆公共卫生关键技术研发与防疫体系建设(2020A03004) （2020A03004）
