帕金森病伴焦虑障碍的神经影像学研究进展OACSTPCD
Research progress in neuroimaging for Parkinson's disease with anxiety disorder
焦虑障碍是帕金森病常见的非运动症状,可出现在病程的任意阶段.由于帕金森病患者的焦虑症状常被运动症状掩盖,且大多诊断依靠主观判断,易被忽视,延误早期干预治疗,降低了帕金森病患者的生活质量.因此,探索帕金森病伴焦虑的发生机制和提高早期诊断率十分重要.随着神经影像学技术不断发展,越来越多的研究证实帕金森病的神经化学性改变与焦虑症状存在相关性.本文就神经影像学技术在帕金森病伴焦虑障碍的病理生理学机制的研究进展作一综述.
Anxiety is a common non-motor symptom of Parkinson's disease,which can occur at any stage of the disease.Due to the fact that the anxiety symptoms of patients with Parkinson's disease are often masked by motor symptoms,and most diagnoses rely on subjective judgment,this symptom is easily overlooked,delaying early intervention and treatment,and reducing the quality of life of Parkinson's disease patients.Therefore,exploring the mechanism of anxiety associated with Parkinson's disease and improving early diagnosis is crucial.With the continuous development of neuroimaging technology,more and more studies have confirmed the correlation between neurochemical changes in Parkinson's disease and anxiety symptoms.This article reviews the research progress of neuroimaging techniques in the pathophysiological mechanisms of Parkinson's anxiety disorder.
李雨欣;徐丙超
南京医科大学连云港临床医学院,江苏 连云港 222000
临床医学
帕金森病非运动症状焦虑神经影像学静息态功能磁共振成像
Parkinson's diseaseNon-motor symptomAnxietyNeuroimagingBlood oxygen level dependent
《中国实用神经疾病杂志》 2024 (007)
920-924 / 5
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