纤维素科学与技术2024，Vol.32Issue(2)：65-71,7.DOI:10.16561/j.cnki.xws.2024.02.09
单纯形重心法复配多糖/纳米纤维素水凝胶
Preparation of Polysaccharide/nanocellulose Hydrogel by Simplex Barycenter Method
摘要
Abstract
In this study,sodium alginate(SA),xanthan gum(XAN),gelatin(G),and nanocellulose(NC)were utilized as encapsulating materials.The simplex barycenter method was employed to optimize the formulation through experimental design.The morphology,texture properties,pH sensitivity and Fourier transform infrared spectroscopy(FT-IR)of the hydrogels were analyzed.The results indicated that the addition of NC increased the viscosity of the hydrogel blend solution,improved the apparent morphology and enhanced the textural properties of the hydrogel,FT-IR showed good compatibility between NC and the polysaccharides.Furthermore,the inclusion of NC increased the swelling ratio of the hydrogel.The polysaccharide/nanocellulose composite hydrogel exhibited excellent pH sensitivity.The theoretical optimal composition was obtained through the simplex barycenter method(SA 19.25%;XAN 24.10%;G 41.00%;NC 15.65%).In conclusion,the final work used the simplex barycenter method to prepare the nanogel with excellent pH sensitivity,capable of stable passage through simulated gastric environments.This provides foundational data for the encapsulation of aerobic probiotics in composite hydrogels and offers a reference for further research and application of hydrogel delivery systems.关键词
多糖基复合水凝胶/pH敏感性/单纯形重心法/理化性质Key words
polysaccharide based complex hydrogel/pH sensitivity/simplex barycenter method/physical and chemical properties分类
医药卫生引用本文复制引用
张紫薇,丛海花,沈益诚,逯晓燕..单纯形重心法复配多糖/纳米纤维素水凝胶[J].纤维素科学与技术,2024,32(2):65-71,7.基金项目
辽宁省教育厅高等学校基本科研项目面上项目(LJKZ0715) （LJKZ0715）
江苏省高职院校教师专业带头人高端研修项目(2023GRFX061) （2023GRFX061）
2022年青年教师科研能力提升计划(BS[2022]18) （BS[2022]18）
江苏省高校"青蓝工程"中青年学术带头人项目. （）
