五行健脾汤加减治疗小儿消化不良脾胃虚弱证的临床效果OA
Clinical Effect of Modified Wuxing Jianpi Decoction on Spleen and Stomach Weakness Syndrome in Children with Dyspepsia
目的:探讨消化不良脾胃虚弱证患儿给予五行健脾汤加减治疗的临床效果.方法:选取2022 年 1 月—2023 年 12 月北京怀柔医院收治的消化不良脾胃虚弱证患儿共计 100 例,以随机数字表法分成研究组(50 例)与对照组(50 例).研究组给予五行健脾汤加减治疗,对照组给予健胃消食片治疗,均治疗 4 周.比较两组临床疗效、症状缓解时间、血清生化指标及胃窦收缩频率.结果:研究组治疗总有效率为 94.00%(47/50),较对照组的 80.00%(40/50)高,差异有统计学意义(P<0.05);研究组症状(食欲不振、腹胀腹痛、恶心呕吐)缓解时间均较对照组早,差异均有统计学意义(P<0.05);治疗后两组胃动素(MTL)、胃泌素(GAS)水平均较治疗前升高,胃蛋白酶原Ⅱ(PGⅡ)水平均较治疗前下降,研究组治疗后的MTL、GAS水平均较对照组高,PGⅡ水平较对照组低,差异均有统计学意义(P<0.05);治疗后两组胃窦收缩频率均较治疗前加快,研究组治疗后较对照组快,差异均有统计学意义(P<0.05).结论:给予消化不良脾胃虚弱证患儿五行健脾汤加减治疗,能够提升临床效果,缩短症状缓解时间,调节血清生化指标水平,改善胃窦收缩频率.
Objective:To investigate the clinical effect of modified Wuxing Jianpi Decoction in the treatment of children with dyspepsia and spleen and stomach weakness.Method:A total of 100 children with dyspepsia with spleen and stomach weakness admitted to Beijing Huairou Hospital from January 2022 to December 2023 were selected and divided into study group(50 cases)and control group(50 cases)by random number table method.The study group was treated with modified Wuxing Jianpi Decoction and the control group was treated with Jianwei Xiaoshi Tablets for 4 weeks.The clinical efficacy,symptom remission time,serum biochemical indexes and frequency of gastric antrum were compared between the two groups.Result:The total effective rate of the study group was 94.00%(47/50),which was higher than 80.00%(40/50)of the control group,the difference was statistically significant(P<0.05).The symptoms(loss of appetite,abdominal distension,abdominal pain,nausea and vomiting)in the study group were relieved earlier than those in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of motilin(MTL)and gastrin(GAS)in both groups were higher than those before treatment,and the levels of pepsinogen Ⅱ(PGⅡ)were lower than those before treatment,after treatment,the levels of MTL and GAS in the study group were higher than those in the control group,and the level of PGⅡ was lower than that in the control group,the differences were statistically significant(P<0.05).After treatment,the frequency of gastric antrum contraction in both groups was faster than those before treatment,and that in the study group was faster than that in the control group,the differences were statistically significant(P<0.05).Conclusion:Treatment with modified Wuxing Jianpi Decoction can improve clinical efficacy,shorten symptom relief time,regulate serum biochemical indicators,and improve frequency of gastric antrum in children with dyspepsia and spleen stomach weakness syndrome.
徐颖奇
北京怀柔医院中医儿科 北京 101300
五行健脾汤小儿消化不良脾胃虚弱证
Wuxing Jianpi DecoctionInfantile dyspepsiaSpleen and stomach weakness syndrome
《中国医学创新》 2024 (017)
71-74 / 4
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