Abstract
Objective:To explore the effects of Chorionic Gonadotropin combined with acupuncture on hormone levels and ovulation rates in patients with polycystic ovary syndrome(PCOS).Method:A total of 78 PCOS patients treated at Ruijin Maternal and Child Health Care Hospital from October 2021 to September 2022 were selected as research subjects,they were randomly divided into a control group(39 cases)and an observation group(39 cases).The control group was treated with oral Clomiphene Citrate Tablets and Ethinylestradiol Cyproterone Tablets,while the observation group was treated with acupuncture and Chorionic Gonadotropin on the basis of Clomiphene Citrate Tablets.Sex hormones[estradiol(E2),testosterone(T),luteinizing hormone(LH),and follicle stimulating hormone(FSH)],ovarian volume,endometrial thickness,cervical mucus score,number of follicles with a diameter(FD)≥12 mm,and the maximum FD of the two groups were compared,ovulation and pregnancy rates,and the incidence of adverse reactions were recorded and compared between the groups.Result:After treatment,the serum E2 level in the observation group was(111.32±33.41)pmol/L,which was higher than(96.59±26.51)pmol/L in the control group,those in both groups were higher compared to those before treatment,the differences were statistically significant(P<0.05).After treatment,the levels of LH,FSH,and T in the observation group were(8.87±2.24)U/L,(5.22±1.19)U/L,and(1.38±0.50)pmol/L,respectively,all lower than(15.14±3.21)U/L,(8.03±1.47)U/L,and(1.87±0.48)pmol/L in the control group,those in both groups were lower compared to those before treatment,the differences were statistically significant(P<0.05).After treatment,the ovarian volume(12.27±2.06)mL,endometrial thickness(10.73±0.98)mm,and cervical mucus score(9.81±2.93)points in the observation group,all were better than(10.84±2.12)mL,(8.34±1.04)mm,(7.24±2.86)points in the control group,the differences were statistically significant(P<0.05).After treatment,the number of follicles(FD)≥12 mm and the maximum FD in the observation group were(8.21±1.58)and(21.30±2.31)mm,respectively,which were better than(5.64±1.12),(17.26±2.44)mm in the control group,the differences were statistically significant(P<0.05).The ovulation and pregnancy rates in the observation group were 92.31%(36/39)and 53.85%(21/39),respectively,significantly higher than 69.23%(27/39)and 23.08%(9/39)in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Chorionic Gonadotropin combined with acupuncture can effectively improve the hormonal levels,and increase the ovulation and pregnancy rates in patients with PCOS.关键词
绒促性素/针灸/多囊卵巢综合征/性激素/促排卵Key words
Chorionic Gonadotropin/Acupuncture/Polycystic ovary syndrome/Hormones/Ovulation induction
