Smart ERA技术评估子宫内膜容受性在不孕症中的应用价值OA

Objective:To explore the effectiveness of Smart ERA technology in evaluating endometrial receptivity for the application in infertility.Method:Clinical data from 76 infertility patients who underwent in vitro fertilization-embryo transfer(IVF-ET)at Ganzhou Women and Children's Health Care Hospital from January 2021 to December 2023 were selected.Based on pregnancy outcomes,patients were divided into a pregnant group(46 cases)and a non-pregnant group(30 cases).The ultrasound diagnostic system was equipped with Smart ERA technology to detect endometrial thickness,endometrial morphology,direction of endometrial movement,sub-endometrial blood flow classification,blood flow of the uterine spiral arteries,endometrial volume,vascularization index(VI),flow index(FI),vascularization flow index(VFI),resistance index(RI)of the spiral arteries,pulsatility index(PI)of the spiral arteries,and the systole/diastole ratio(S/D),utilizing ROC curves to predict pregnancy outcomes in infertility patients.Result:The RI of the spiral arteries,PI of the spiral arteries,and S/D values were significantly lower in the pregnant group than those in the non-pregnant group(P<0.05),while endometrial volume,VI,FI and VFI were significantly higher in the pregnant group than those in the non-pregnant group(P<0.05).No significant differences were observed between the two groups in terms of endometrial thickness,morphology,direction of movement,and sub-endometrial blood flow classification(P>0.05).The areas under the curve for predicting pregnancy outcomes based on RI of the spiral arteries,PI of the spiral arteries,S/D,VI,FI,VFI and endometrial volume were 0.818,0.789,0.897,0.904,0.896,0.983 and 0.780 respectively.Conclusion:Ultrasound parameters effectively assess endometrial receptivity and predict pregnancy outcomes in infertility patients.These findings support the application value of Smart ERA technology in the assessment and treatment of infertility.