中国食品添加剂2024，Vol.35Issue(6)：193-202,10.DOI:10.19804/j.issn1006-2513.2024.6.025
新型超交联聚合物在蜂蜜中抗生素残留的检测研究
Detection of antibiotic residues in honey by novel hypercrosslinked polymers
摘要
Abstract
In order to achieve simultaneous determination of various antibiotic residues in honey and optimize the pre-treatment process,a novel porous organic polymer material(POP)was synthesized and applied to detect 11 antibiotic residues in honey.The pre-treatment was carried out using a porous polymer material dispersion adsorption method.Liquid chromatography tandem mass spectrometry was performed with a 0.1%(v/v)formic acid aqueous solution and acetonitrile as the mobile phase for elution.The AtiantisR T3 column(2.1 mm x 50 mm,1.7 μm)was used for separation of antibiotics residues,and the 11 antibiotics achieved good separation results within 4 minutes.Tetracyclines,sulfonamides,and quinolones had good linear relationships within the range of 10 to 500,2 to 100,and 1 to 50 μg/L,respectively.Their limits of detection were 3.0,0.6,and 0.3 μg/kg,respectively.Their limits of quantification reached 10.0,2.0,and 1.0 μg/kg,respectively.The average recovery rates of 11 antibiotics under low,medium,and high levels of spiking were 90.9%to 108.7%,with a relative standard deviation of 2.1%to 9.4%.Compared with the traditional solid-phase extraction purification method,this detection method with POP had the characteristics of operation convenience,energy-saving,and high efficiency,and with good repeatability and high recovery rate,it can be used for the detection of various antibiotic residues in honey.关键词
超交联聚合物材料/合成方法/抗生素残留检测/蜂蜜Key words
hypercrosslinked polymer/synthetic method/antibiotics residues detection/honey分类
轻工纺织引用本文复制引用
王安琪,张斌骏,秦宇,张申平..新型超交联聚合物在蜂蜜中抗生素残留的检测研究[J].中国食品添加剂,2024,35(6):193-202,10.基金项目
上海市质量监督检验技术研究院项目(KY-2020-9-SP) （KY-2020-9-SP）
