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体外开窗技术治疗主动脉弓部病变的中期效果OA北大核心CSTPCD

Midterm outcomes of surgeon-modified fenestrated stent-graft for aortic arch pathologies

中文摘要英文摘要

目的:探究胸主动脉腔内修复术(thoracic endovascular aortic repair,TEVAR)联合左锁骨下动脉(left subclavian artery,LSA)体外开窗技术治疗主动脉弓部病变的中期效果.方法:选择2018年1月—2021年12月南京医科大学第一附属医院收治的111例行TEVAR联合LSA体外开窗技术治疗的患者,回顾性分析其围术期以及中期随访的临床材料.结果:手术成功率为100%(111/111),30d内病死率为3.6%(4/111),术后中位随访时间为33.0个月,全因病死率为6.3%(7/111),主动脉相关的病死率为2.7%(3/111),主要并发症中脑血管意外3例(2.7%),截瘫2例(1.8%),近端逆撕形成A型主动脉夹层1例(0.9%),支架内漏2例(1.8%),支架移植物引起远端新发破口 3例(2.7%).进行主动脉二次干预的有4例(3.6%),其中3例(2.7%)腔内手术,1例(0.9%)开胸行人工血管置换手术.结论:TEVAR联合LSA体外开窗技术治疗主动脉弓部病变的中期效果在可接受的范围内,但是仍缺乏长期的观察结果数据.此外,开窗技术流程亟待规范统一,相关设备也待进一步开发.

Objective:To investigate the midterm outcomes of thoracic endovascular aortic repair(TEVAR)combined with left subclavian artery(LSA)fenestration for aortic arch diseases.Methods:We retrospectively analyzed the perioperative period and midterm follow-up clinical data of 111 patients who underwent TEVAR combined with LSA fenestration in the First Affiliated Hospital of Nanjing Medical University from January 2018 to December 2021.Results:Overall,the success rate of the surgery was 100%(111/111),the mortality rate within 30 days was 3.6%(4/111).The median postoperative follow-up time was 33.0 months,the all-cause mortality was 6.3%(7/1 11),the aorta-related mortality was 2.7%(3/1 11).Among the main complications,there were 3 patients(2.7%)of cerebrovascular accident,2 patients(1.8%)of paraplegia,1 patient(0.9%)of retrograde type A dissection(RTAD),2 patients(1.8%)of endoleak,and 3 patients(2.7%)of distal stent-induced new entry(dSINE).Four patients(3.6%)underwent the second aortic intervention,of which 3 patients(2.7%)were performed endovascular surgery and 1 patient(0.9%)was performed thoracotomy and artificial vascular replacement.Conclusion:The mid-term outcomes of TEVAR combined with LSA fenestration for aortic arch diseases were within the acceptable range,however,further follow-up results are needed and long-term stability and durability needs to be assessed.In addition,the technical process of fenestration needs to be standardized and unified,and related equipment needs to be further developed.

李钢;徐心阳;刘鸿;李明辉;顾嘉玺;倪布清

南京医科大学第一附属医院心脏大血管外科,江苏 南京 210029

临床医学

主动脉夹层主动脉腔内修复术体外开窗技术左锁骨下动脉支架内移植物

aortic dissectionthoracic endovascular aortic repairin vitro fenestrationleft subclavian arteryendovascular graft

《南京医科大学学报(自然科学版)》 2024 (007)

966-971 / 6

南京医科大学专病联盟公益项目(NMU2023SD101)

10.7655/NYDXBNSN240127

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