中国畜牧杂志2024，Vol.60Issue(7)：6-12,7.DOI:10.19556/j.0258-7033.20230914-08
基因编辑技术及其在畜禽遗传育种中的应用研究进展
Research Progress on Gene Editing Technology and Its Application in Livestock and Poultry Genetic Breeding
摘要
Abstract
Gene editing technology refers to the modification of specific DNA sequences in the genome to cause targeted,heritable changes in animal traits.At present,the main gene editing technologies include zinc finger nucleases(ZFNs),transcription activator-like effector nucleases(TALENs),clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9(CRISPR/Cas9).Application of gene editing technologies with efficient and precise genome manipulation in domestic animals could improve production,quality and disease resistance traits.In this paper,we summarized the development history and principles of gene editing technologies as well as their applications in domestic animals genetic breeding thereby providing references for animal gene editing breeding.关键词
基因编辑/畜禽/ZFNs/TALENs/CRISPR/Cas9Key words
Gene editing/Domestic animal/ZFNs/TALENs/CRISPR/Cas9分类
农业科技引用本文复制引用
曹慧,韩博,孙东晓..基因编辑技术及其在畜禽遗传育种中的应用研究进展[J].中国畜牧杂志,2024,60(7):6-12,7.基金项目
国家重点研发计划项目(2021YFF1000700) （2021YFF1000700）
教育部创新团队发展计划(IRT_15R62) （IRT_15R62）
