从"精筋失衡论"探讨近视发病的"脑-目"机制OA北大核心CSTPCD
Discussion on the"brain-eye"mechanism of myopia from the"theory of imbalance of the essence and tendon"
近视作为全球重大健康问题,其发病机制尚不明确,且缺乏高效、可推广的治疗措施.我国儿童、青少年的近视率居高不下,防控形势严峻."精筋失衡论"认为,"精筋失衡"可导致眼部精血不能通行于目,眼部经筋舒缩延迟,导致视物不清.现代研究表明,近视的发展过程中多个脑区微结构及其激活范围与信号均出现明显变化,为"脑-目"机制奠定了生物学基础.同时,大脑核团活跃性异常引起脉络膜血流改变与眼肌调节下降均加速近视的发生、发展,是"脑-目"失衡的体现.故近视的治疗应以补肾精、充脑髓为核心,以补肝血、柔经筋为重点,充盈脑目精血,保持目之筋张弛有度,增强眼的调节功能,维持目之筋刚强有力,可延缓眼轴变长,从而防止近视的进展,可以丰富中医适宜技术从脑防控近视的科学内涵,为探索中医药防治近视提供思路.
Myopia is a significant global health issue,and its exact causes are still not fully understood,leaving a lack of effective and propaqable treatment options.The prevalence of myopia among children and adolescents in China remains high,posing challenges for prevention and control efforts.According to the"theory of imbalance of essence and tendon",an imbalance in the essential elements and tendons can impede the passage of eye essence and blood,resulting in delayed expansion and contraction of the eye meridians and tendons,leading to blurred vision.Modern research indicates that during the development of myopia,there are notable changes in the microstructure,activation range,and signaling of various brain regions,providing a biological basis for the"brain-eye"mechanism.Moreover,abnormal activity in the brain nucleus contributes to alterations in choroid blood flow and the impairment of eye muscle regulation,thereby accelerating the progression of myopia,this phenomenon represents the manifestation of the brain-eye imbalance.Consequently,strategies for myopia prevention and control should prioritize nourishing kidney essence,replenishing brain marrow,promoting liver and blood health,and softening the meridians.These measures aim to optimize the functioning of the brain and eyes,maintain the flexibility of eye tendons,enhance eye regulation,sustain the strength of eye tendons,and delay the advancement of eye axis growth and myopia.By enriching the scientific understanding of the appropriate application of traditional Chinese medicine techniques to prevent and control myopia through the brain,this research provides valuable insights for future explorations in this field.
李丹玉;亢泽峰;晏鑫;孙宏睿;李宝花;刘梦雨;侯昕玥;彭华
中国中医科学院眼科医院 北京 100040||全国中医药儿童青少年近视防治中心云南省第二人民医院
中医学
近视精筋失衡脑科学
myopiaessencetendonimbalancebrain science
《北京中医药大学学报》 2024 (007)
971-976 / 6
国家重点研发计划项目(No.2022YFC3502500,No.2022YFC3502505);中医药传承与创新"百千万"人才工程(岐黄工程)岐黄学者;中国中医科学院科技创新工程重点协同攻关项目(No.CI2022C001);云南省科技计划项目(No.202105AF150044) National Key R&D Program of China(Nos.2022YFC3502500 and 2022YFC3502505)
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