从脾肾分期论治帕金森病便秘OACSTPCD

Constipation stands as one of the most prevalent gastrointestinal symptoms among non-motor manifestations in Parkinson's Disease(PD),featuring a notably high incidence that gravely impairs patients'quality of life.Fundamentally,the etiology of constipation in PD revolves around the withering of sinews and vessels and the vacuity of brain marrow.In its early phase,the mechanism involves a gradual depletion of the spleen's qi alongside blockage of bowel qi.Progressing into the mid-to-late stages,the pathology evolves to encompass fluid deficiency causing intestinal dryness and a decline in kidney essence.A characteristic pattern of syndrome development entails the incremental weakening of the spleen qi,which in turn impacts the kidney over time.From a clinical perspective,management can be stratified according to disease progression:in the initial stage,therapy should emphasize invigorating qi to activate the spleen,promoting qi circulation to resolve stagnation;during the intermediate phase,the focus shifts to moistening the intestines for smoother bowel movements and safeguarding yin fluids;whereas in advanced stages,replenishing kidney essence and gently facilitating the passage of accumulated waste becomes paramount.This strategy adheres to the holistic and dynamic principles of traditional Chinese medicine in tackling the complex presentation of PD-related constipation.