神经损伤与功能重建2024，Vol.19Issue(7)：419-423,5.DOI:10.16780/j.cnki.sjssgncj.20230053
中西医论治放射性脑损伤
Treatment of Radiation-Induced Brain Injury by Traditional Chinese and Western Medicine
李炎辉 1武鑫 2王坦 1王冬慧 3张晗 3高剑峰3
作者信息
- 1. 河南中医药大学医学院 郑州 450046||河南中医药大学病理学与病理生理学教研室 郑州 450046
- 2. 河南中医药大学医学院 郑州 450046||河南中医药大学生理学教研室 郑州 450046
- 3. 河南中医药大学医学院 郑州 450046
- 折叠
摘要
Abstract
Radiation-induced brain injury(RBI)is one of the severe complications arising from the radiotherapy of head and neck malignant tumors,characterized by significant cognitive decline and impaired learning and memory.It adversely affects patients'quality of life and can even be life-threatening in severe cases.The pathogenesis of RBI remains unclear,but it may be related to factors such as cerebrovascular injury,glial cell injury,inflammatory responses and free radical injury.Traditional Chinese medicine(TCM)attributes RBI as a consequence of the body's inherent weakness and the invasion nature of radiation,which is clinically manifested as a condition of original deficiency and solid injury.In addition to symptomatic treatment in Western medicine,TCM therapy has been progressively incorporated into clinical practice.Recent studies have focused on synaptic plasticity to elucidate the underlying mechanisms,offering novel perspectives and a theoretical foundation for advancing the role of TCM in the treatment of RBI.This article reviews the latest literature on the pathogenesis and treatment of RBI from the perspectives of both traditional Chinese and Western medicine.关键词
放射性脑损伤/突触可塑性/机制/治疗Key words
radiation-induced brain injury/synaptic plasticity/mechanism/treatment分类
医药卫生引用本文复制引用
李炎辉,武鑫,王坦,王冬慧,张晗,高剑峰..中西医论治放射性脑损伤[J].神经损伤与功能重建,2024,19(7):419-423,5.
