食品工业科技2024，Vol.45Issue(15)：429-442,14.DOI:10.13386/j.issn1002-0306.2023090148
石斛多糖的结构特征、生物活性、构效关系及产品开发进展
Research Progress on Structure Characteristics,Biological Activity,Structure-Activity Relationship and Product Development of Dendrobium Polysaccharides
摘要
Abstract
Dendrobium is a traditional,valuable,and nourishing medicinal herb in China.It benefits the stomach,promotes fluid production,nourishes Yin,and clears heat.Polysaccharides are among the main active ingredients of Dendrobium.By reviewing literature over the past decade,the common structures and biological activities of Dendrobium polysaccharides are systematically summarized.The results illustrate that Dendrobium polysaccharides possess various effects,including antioxidant,antitumor,anti-inflammatory,and immunoregulatory effects,gut microbiota modulation,blood sugar reduction,and anticataract properties.The chemical structures of these polysaccharides are closely related to their biological activities.Previous studies suggest that polysaccharides rich in mannose and glucose exhibit stronger activity,whereas higher acetylation levels enhance immune activity.Higher uronic acid content corresponds to greater antioxidant ability,which may be due to the presence of(1→4)-α-D-Glcp and(1→4)-α-D-Manp on the main chain.Additionally,chemical modifications such as sulfation,selenization,and acetylation can enhance activity,whereas carboxymethylation decreases it.This article summarizes the research progress in recent years on the structure,biological activity,and product development of Dendrobium polysaccharides both home and abroad,elucidating the structure-activity relationship,aiming to provide important references for their in-depth development and application.关键词
石斛多糖/结构特征/生物活性/构效关系/产品Key words
Dendrobium polysaccharides/structure characteristics/biological activity/structure-activity relationship/product分类
轻工纺织引用本文复制引用
罗昭勇,姜艳,余晓历,柳静蕾,李博宁,章柯莹,王淑玲,谢恬..石斛多糖的结构特征、生物活性、构效关系及产品开发进展[J].食品工业科技,2024,45(15):429-442,14.基金项目
国家自然科学基金(82074052) （82074052）
浙江省中医药科技计划重点研究项目(2022ZZ024) （2022ZZ024）
山东省自然科学基金联合基金重点支持项目(2021LZY039) （2021LZY039）
济南市"新高校20条"引进创新团队项目(202333021). （202333021）
