食品科学2024，Vol.45Issue(13)：312-324,13.DOI:10.7506/spkx1002-6630-20230522-203
组学技术研究裂殖壶菌高产二十二碳六烯酸的进展
Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by Aurantiochytrium
摘要
Abstract
Docosahexaenoic acid(DHA)is an n-3 polyunsaturated fatty acid that is essential for human nutrition.Currently,DHA is commonly produced using Aurantiochytrium,and omics technologies are widely used to investigate the mechanism underlying high DHA production in Aurantiochytrium,providing a foundation for genetic modification of Aurantiochytrium and control of the fermentation process.In this article,the history and major research directions of DHA production by Aurantiochytrium are summarized,and the application of omics technology in Aurantiochytrium is reviewed.It also summarizes recent progress in the application of genomics,transcriptomics,proteomics,metabolomics and multi-omics approaches as well as mathematical models based on omics data to reveal the mechanism underlying high DHA production in Aurantiochytrium.This review concludes with a discussion of future prospects for the development and application of omics technology.关键词
裂殖壶菌/基因组学/转录组学/蛋白质组学/代谢组学Key words
Aurantiochytrium/genomics/transcriptomes/proteomics/metabolomics分类
轻工纺织引用本文复制引用
张华秋,杨莹莹,刘丽萍,姚明静,韩墨,张家祥,赵祥颖..组学技术研究裂殖壶菌高产二十二碳六烯酸的进展[J].食品科学,2024,45(13):312-324,13.基金项目
山东省重点研发计划(重大科技创新工程)项目(2020CXGC010604) （重大科技创新工程）
齐鲁工业大学(山东省科学院)科教产重大创新专项(2022JBZ01-08) （山东省科学院）
