食品与发酵工业2024，Vol.50Issue(13)：323-330,8.DOI:10.13995/j.cnki.11-1802/ts.036544
利用非产溶剂梭菌合成生物丁醇研究进展
Recent advances on the synthesis of biobutanol by non-solvent microorganisms
摘要
Abstract
As an important bulk chemical and potential biofuel,butanol has a wide range of applications in many fields.The depletion of fossil fuels and the progress of synthetic biotechnology have renewed interest in the production of biobutanol.Solvent-producing Clostridi-um is commonly used to produce butanol through traditional acetone-butanol-ethanol(ABE)fermentation.However,its relatively slow growth rate,low butanol tolerance and production efficiency hinder its further application.Recently,researchers have studied some other promising industrial hosts as the chassis to produce butanol,including Escherichia coli,Saccharomyces cerevisiae,C.tyrobutyricum and so on.This review comprehensively summarizes the advantages and challenges of different non-solvent strains for the production of butanol,in order to better determine the ideal non-solvent host for the production of butanol.In addition,a strategy to further increase the production of butanol was also proposed.关键词
丁醇/非产溶剂微生物/丙酮-丁醇-乙醇发酵/代谢工程Key words
butanol/non-solvent-producing microorganisms/ABE fermentation/metabolic engineering引用本文复制引用
于乐永,于海瑞,赵有志,王利华,袁紫乙,庄文静..利用非产溶剂梭菌合成生物丁醇研究进展[J].食品与发酵工业,2024,50(13):323-330,8.基金项目
山东省重大科技创新工程项目(2018CXGC0102,2019JZZY020710) （2018CXGC0102,2019JZZY020710）
