食品与发酵工业2024,Vol.50Issue(14):196-204,9.DOI:10.13995/j.cnki.11-1802/ts.036487
青熟期托克逊杏咀嚼片对小鼠肠胃功能的影响
Effects of green ripe period Tuokexun apricot chewable tablets on gastrointestinal function in mice
摘要
Abstract
This study aimed to investigate the effect of homemade green ripe period chewing tablets on gastrointestinal function in mice.The free combination of Kunming mice was divided into a blank control group,a positive control group,a model control group,a green ripe period Tuokexun apricot fruit group,a low-dose group of green ripe period Tuokexun apricot chewable tablets,a medium dose group of green ripe period Tuokexun apricot chewable tablets,and a high-dose group of green ripe period Tuokexun apricot chewable tab-lets.After 7 days of adaptive feeding,loperamide hydrochloride was used in the mouse model of constipation,through studies of gastroin-testinal function in mice,the effects of first blue stool time,the number of defecation grains,fecal moisture content,small bowel propul-sion rate,colon water content,and gastric emptying rate were obtained.Results showed that there were significant differences in various indicators between the low,medium,and high dose groups of the green ripening stage Tuokexun apricot chewing tablets and the constipa-tion model control group,positive control group,and green ripening stage Tuokexun apricot fruit group.This indicated that the green ripe period Tuokexun apricot chewing tablets could significantly improve the small intestine propulsion rate,shorten the defecation time,in-crease the number of defecated particles in 6 hours,increase gastric emptying rate,fecal water content,and colon water content in consti-pation model mice,through deeply studying the laxative mechanism,showing that it could regulate the content of P substance and vasoac-tive intestinal peptide,promote intestinal peristalsis,and improve constipation.关键词
青熟期托克逊杏/咀嚼片/润肠通便/便秘/小鼠Key words
green ripe period Tuokexun/chewable tablet/relaxing bowel/constipation/mice引用本文复制引用
王晨,尼格尔热依·亚迪卡尔,冯作山,李硕,杨莲,古丽米热·努尔麦麦提,白羽嘉..青熟期托克逊杏咀嚼片对小鼠肠胃功能的影响[J].食品与发酵工业,2024,50(14):196-204,9.基金项目
新疆杏产业技术体系专项资金项目(XJCYTX-03-05-2021) (XJCYTX-03-05-2021)
新疆农业大学研究生科研创新计划项目(XJAUGRI2023047) (XJAUGRI2023047)