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蜂胶脂质体制备工艺优化及抗氧化活性分析

孙思源 孔令杰 朱和权 董捷

食品与机械2024,Vol.40Issue(6):192-198,232,8.
食品与机械2024,Vol.40Issue(6):192-198,232,8.DOI:10.13652/j.spjx.1003.5788.2023.81037

蜂胶脂质体制备工艺优化及抗氧化活性分析

Optimization of the preparation process for propolis liposome and antioxidant activity analysis

孙思源 1孔令杰 1朱和权 1董捷1

作者信息

  • 1. 中国农业科学院蜜蜂研究所资源昆虫高效养殖与利用全国重点实验室,北京 100093
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摘要

Abstract

[Objective]This study aimed to improve the water solubility of propolis,and expand the application of propolis in food industry.[Methods]By utilizing the film dispersion method,propolis liposome was prepared with cholesterol and soy lecithin as the wall material and propolis as the core component.The optimal preparation process for propolis liposome was optimized through a combination of one-factor experiments and response surface methodology with the encapsulation rate as the test index,and its antioxidant activity was also analyzed and evaluated.[Results]The optimal process for preparing propolis liposome consisted of 2.5 g/100 mL soy lecithin,a cholesterol to soy lecithin ratio of 1∶10.3,and a cholesterol to propolis ratio of 1∶3.8.These optimized conditions resulted in a high encapsulation rate of 93.09%for propolis liposome.In addition,it was found that the scavenging efficiencies of the 50 μL/mL propolis liposome were 88.60%,60.53%,and 82.25%for clearance of DPPH radicals,ABTS+radicals,and hydroxyl radicals,respectively.[Conclusion]The prepared propolis liposome has high encapsulation efficiency,good water solubility and good antioxidant capacity.

关键词

蜂胶/脂质体/薄膜分散法/抗氧化活性

Key words

propolis/liposome/film dispersion method/antioxidant activity

引用本文复制引用

孙思源,孔令杰,朱和权,董捷..蜂胶脂质体制备工艺优化及抗氧化活性分析[J].食品与机械,2024,40(6):192-198,232,8.

基金项目

国家蜂产业技术体系(编号:CARS-44-KXJ19) (编号:CARS-44-KXJ19)

中国农业科学院创新工程(编号:CAAS-ASTIP-2019IAR) (编号:CAAS-ASTIP-2019IAR)

食品与机械

OA北大核心CSTPCD

1003-5788

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