武警医学2024，Vol.35Issue(7)：567-571,577,6.
脾硬化性血管瘤样结节性转化的临床病理特征
Clinicopathological features of sclerosing angiomatoid nodular transformation
于兰 1丁会珍 2高逸群 3路平 3张静4
作者信息
- 1. 100048 北京,解放军总医院第六医学中心:消化内科
- 2. 100037 北京,解放军总医院第四医学中心病理科
- 3. 100048 北京,解放军总医院第六医学中心:病理科
- 4. 100048 北京,解放军总医院第六医学中心:放射诊断科
- 折叠
摘要
Abstract
Objective To investigate the clinicopathological features of sclerosing angiomatoid nodular transformation(SANT).Methods Clinical data of SANT patients in the Fourth and Sixth Medical Center of PLA General Hospital from 2016 to 2022 were collected,and the clinicopathological features,imaging features and immunohistochemical data were analyzed.Results A total of 7 cases were found,including 5 males and 2 females,aged 32-49 years with an average age of 42.3 years.Six cases were single,with a maximum diameter of 3.0-14.5 cm(average 7.4 cm),and 1 case was multiple,with a maximum diameter of 5.7 cm×5 cm×3.5 cm,with a minimum diameter of 0.7 cm×0.6 cm×0.6 cm.Microscopically,there were multiple hemangiomatous nodules sur-rounded by fibers.The vascular components in the nodules were complex,which were like splenic sinus,capillary or venous.The ex-pressions of CD34,CD31,and CD8 in vascular endothelial cells were different.The SMA expression in peripheral spindle cells was fo-cally positive.EBER detection results of in situ hybridization were negative.Conclusions SANT is a rare benign vascular lesion with unique pathological features,which has no clinical symptoms and is easy to be misdiagnosed.It can be cured by surgical resection.Postoperative pathological morphology and immunohistochemical staining are important methods for definite diagnosis.关键词
脾脏/脾硬化性血管瘤样结节性转化/临床病理/鉴别诊断Key words
spleen/sclerosing angiomatoid nodular transformation/clinical pathology/differential diagnosis分类
医药卫生引用本文复制引用
于兰,丁会珍,高逸群,路平,张静..脾硬化性血管瘤样结节性转化的临床病理特征[J].武警医学,2024,35(7):567-571,577,6.
