协和医学杂志2024，Vol.15Issue(4)：968-972,5.DOI:10.12290/xhyxzz.2024-0208
恶性胰岛素瘤多发肝转移一例
Multiple Liver Metastases in Malignant Insulinoma:A Case Report
廖晋豪 1高玉婷 1王湘 2王志伟 3徐强 4赵宇星 1池玥 1茅江峰 1阳洪波1
作者信息
- 1. 中国医学科学院北京协和医院 内分泌科国家卫生健康委员会内分泌重点实验室,北京 100730
- 2. 中国医学科学院北京协和医院 肿瘤内科,北京 100730
- 3. 中国医学科学院北京协和医院 放射科,北京 100730
- 4. 中国医学科学院北京协和医院 基本外科,北京 100730
- 折叠
摘要
Abstract
Malignant insulinoma is a kind of rare and challenging neuroendocrine tumor.It is often ac-companied by distant metastasis,among which liver metastasis is most common,and the prognosis is often non-promising.In this paper,we report a case of multiple liver metastases from malignant insulinoma.The pa-tient,a 70-year-old male,was admitted to the hospital due to"episodic consciousness disorder for more than four months."Blood glucose monitoring revealed recurrent hypoglycemia in the early morning,after meals,and at night.Pancreatic perfusion CT and dynamic enhanced MRI of the liver revealed a mass in the uncinate process of the pancreatic head and multiple liver metastases.Percutaneous liver biopsy confirmed the diagnosis of insulinoma.After multidisciplinary discussions,hepatic artery embolization and radiofrequency ablation were performed in stages,in combination with everolimus treatment.Thereafter,the enhanced CT demonstrated that some liver metastases shrank.The patient had regular meals,and the blood sugar gradually increased and re-mained normal thereafter.This article discusses this case's clinical characteristics and multidisciplinary collabo-rative diagnosis and treatment,aiming to provide experience for the comprehensive clinical diagnosis and treat-ment of malignant insulinoma patients.关键词
低血糖症/恶性胰岛素瘤/多学科协作诊疗Key words
hypoglycemia/malignant insulinoma/multidisciplinary treatment分类
医药卫生引用本文复制引用
廖晋豪,高玉婷,王湘,王志伟,徐强,赵宇星,池玥,茅江峰,阳洪波..恶性胰岛素瘤多发肝转移一例[J].协和医学杂志,2024,15(4):968-972,5.
