中国输血杂志2024，Vol.37Issue(7)：721-727,7.DOI:10.13303/j.cjbt.issn.1004-549x.2024.07.001
人类白细胞抗原基因分型方法分辨水平的专家共识
Expert consensus on the resolution level of the methods for HLA genotyping
中国血小板基因数据库协作组 1浙江省血液中心 1朱发明1
作者信息
摘要
Abstract
Human leukocyte antigen(HLA)genotyping has been widely used in establishing the database of the donors for hematopoietic stem cell,HLA matching selection between the donor and recipient,establishing the database of platelet donors with known HLA genotype,diagnosis of HLA association with diseases,genetics study and other scientific research.With the increasing number of HLA alleles and the development of HLA genotyping technology,there are some controversy in the definition of resolution for HLA genotyping,the description of the results for HLA genotyping between donor and re-cipient and the determination of HLA matching level.In order to improve the normalization of the definition and interpreta-tion of HLA genotyping resolution,this expert consensus is formulated by many experts from the fields of HLA genotyping in the laboratory and clinical transplantation according to the relevant domestic and foreign literature and clinical practice.The definition of the resolution of HLA genotyping,the methods of HLA genotyping,the description of the results between donor and recipient and HLA matching determination are summarized,which will further standardize HLA genotyping technology and ensure the accuracy of the results for HLA genotyping.关键词
人类白细胞抗原/等位基因/基因分型方法/分辨水平/描述方式Key words
human leukocyte antigen/allele/genotyping method/resolution level/description mode分类
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中国血小板基因数据库协作组,浙江省血液中心,朱发明..人类白细胞抗原基因分型方法分辨水平的专家共识[J].中国输血杂志,2024,37(7):721-727,7.
