肝穿刺活检在儿童遗传代谢性肝病中的诊断价值OA北大核心CSTPCD

Inherited metabolic liver disease is a kind of common liver disease in children.Although the prevalence rate of single disease is low,the overall incidence is high.The diagnosis relies on multiple clinical data,including clinical symptoms and signs,laboratory examination,imaging,liver biopsy and gene detection.Liver biopsy is an invasive procedure,and its diagnostic value is not consistent in different genetic metabolic liver diseases.Not all liver diseases need liver biopsy,and genetic metabolic liver diseases do not necessarily have their characteristic pathological manifestations.Therefore,clinicians should master the indications strictly to maximize the clinical value of liver biopsy.