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从"脾主升清"探讨瓦伯格效应在学习记忆障碍中的作用OACSTPCD

Discussion on the Role of Warburg Effect in Learning and Memory Disorders Based on the Theory of"Spleen Governing the Ascendant of Usable Substances"

中文摘要英文摘要

学习记忆障碍病位主要在脑,与脾、心、肾、肝功能失调密切相关,尤其是脾,其居中土,主管气机升降,斡旋一身之气血以濡养脑窍.本文通过论述"脾主升清"的生理功能,探讨其在学习记忆障碍中的作用.瓦伯格效应以快速高效的方式产生能量以维持大脑正常功能,与中医脾主升清的功能在一定程度上相契合.因此,以"脾主升清"立论,探讨学习记忆障碍的病理基础,并从中西医方面阐述瓦伯格效应紊乱是本病的重要特征,有助于深入探讨助脾升清法治疗学习记忆障碍的作用,为该病中医治疗提供新思路.

The main pathogenesis of learning and memory disorders lies in the brain,closely related to dysfunction of the spleen,heart,kidney,and liver,especially concerning the spleen,which governs the ascending and descending of qi and facilitates the circulation of qi and blood throughout the body to nourish the brain.This article discussed the physiological function of"spleen governing the ascendant of usable substances"and explored its role in learning and memory disorders.The Warburg effect generates energy rapidly and efficiently to maintain normal brain function,which to some extent aligns with the function of the spleen governing the ascendant of usable substances in TCM.Therefore,by emphasizing the role of"spleen governing the ascendant of usable substances",this article explored the pathological basis of learning and memory disorders.It also discussed the disruption of the Warburg effect was an important feature of this condition from both TCM and Western medicine perspectives,which could help to explore in depth the role of the method of promoting spleen in governing the ascendant of usable substances in the treatment of learning and memory disorders,and provide new ideas for its TCM treatment.

唐志娟;周雯;战丽彬

南京中医药大学中医学院·中西医结合学院,江苏 南京 210023辽宁中医药大学中医药创新工程技术中心,辽宁 沈阳 110847||辽宁省中医脾脏象现代研究重点实验室,辽宁 沈阳 110847

中医学

脾主升清瓦伯格效应学习记忆障碍助脾升清法

spleen governing the ascendant of usable substancesWarburg effectlearning and memory disordermethod of promoting spleen in governing the ascendant of usable substances

《中国中医药信息杂志》 2024 (008)

12-16 / 5

国家自然科学基金青年科学基金(82104703);国家中医药领军人才支持计划-岐黄学者(2022年);江苏省自然科学基金青年基金(BK20210688)

10.19879/j.cnki.1005-5304.202308546

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