中医药信息2024，Vol.41Issue(7)：38-41,4.DOI:10.19656/j.cnki.1002-2406.20240708
基于"肾主骨"理论探讨肠道微生态与骨质疏松症的相关性
Exploring the Relationship between Gut Microbiota and Osteoporosis Based on the Theory of"Kidney Governing Bones"
摘要
Abstract
With the rapid development of molecular biology,the relationship between gut microbiota and osteoporosis(OP)has become a hot topic in clinical research.Traditional Chinese medicine(TCM)has theoretical support in the treatment of OP based on the theory of"kidney governing bones",but it has not yet received sufficient validation from modern medicine.Therefore,starting from the theory of"kidney governing bones"and focusing on gut microbiota,this paper discusses the relationship between kidney deficiency and OP.It is found that OP patients are prone to gut microbiota imbalance,and disturbances in gut microbiota can accelerate the progression of OP through pathways such as neuroinflammation,short-chain fatty acids,and intestinal barrier disruption.关键词
肾主骨/肠道微生态/骨质疏松症Key words
Kidney governing bones/gut microbiota/osteoporosis引用本文复制引用
杨青峰,张翔,刘耀忠,刘佳瑞,吕文飞,赵川槐,王晓宇,蒋宜伟..基于"肾主骨"理论探讨肠道微生态与骨质疏松症的相关性[J].中医药信息,2024,41(7):38-41,4.基金项目
国家自然科学基金项目(82160916) （82160916）
内蒙古自治区重点研发和成果转化项目(2023YFSH0049) （2023YFSH0049）
