Apolipoprotein A-I binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegenerationOA
Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs worldwide.Due to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more prevalent.Glaucoma primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.
Sinwoo Hwang;Seunghwan Choi;Soo-Ho Choi;Keun-Young Kim;Yury I.Miller;Won-Kyu Ju;
Hamilton Glaucoma Center and Shiley Eye Institute,The Viterbi Family Department of Ophthalmology,University of California San Diego,La Jolla,CA,USAHamilton Glaucoma Center and Shiley Eye Institute,The Viterbi Family Department of Ophthalmology,University of California San Diego,La Jolla,CA,USA Department of Medicine,University of California San Diego,La Jolla,CA,USANational Center for Microscopy and Imaging Research,Department of Neurosciences,University of California San Diego,La Jolla,CA,USADepartment of Medicine,University of California San Diego,La Jolla,CA,USA
临床医学
irreversiblepassprimarily
《Neural Regeneration Research》 2025 (005)
P.1414-1415 / 2
supported by the National Institutes of Health grants EY034116 (to WKJ, KYK, and SHC) and AG081037 (to YIM and WKJ)。
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