华西口腔医学杂志2024，Vol.42Issue(4)：476-480,5.DOI:10.7518/hxkq.2024.2023450
瑞马唑仑在阻生牙拔除术中的应用
Advantages of remimazolam for sedation in impacted tooth extraction
摘要
Abstract
Objective This study aims to compare the sedative effects of remimazolam and midazolam during im-pacted tooth extraction to provide a comfortable sedation treatment for patients with dental anxiety.Methods A pro-spective randomized controlled trial was conducted,in which 60 patients undergoing intravenous sedation for mandibular impacted third molar extraction were evenly divided into either the remimazolam or midazolam group.Prior to receiving a nerve blocker,the patients were sedated with remimazolam or midazolam.Various parameters were recorded and ana-lyzed,including onset time,awakening time,recovery time,modified dental anxiety scale(MDAS)scores before and af-ter surgery,patient-doctor satisfaction levels,postoperative side effects within 24 hours,heart rate(HR),and mean arteri-al pressure(MAP)at different time points.Results Compared with the midazolam group,patients in the remimazolam group demonstrated significantly shorter onset,awakening,and recovery times as well as lower postoperative MDAS scores and higher levels of patient-doctor satisfaction.Fewer postoperative side effects were reported in the remimazol-am group,although the differences were not statistically significant.Conclusion The use of remimazolam demon-strates faster onset and recovery,superior efficacy in reducing dental anxiety,and enhanced satisfaction among patients and doctors,thereby presenting distinct advantages for sedation treatment for patients with dental anxiety.关键词
瑞马唑仑/咪达唑仑/牙拔除术/牙科焦虑Key words
remimazolam/midazolam/tooth ex-traction/dental anxiety分类
医药卫生引用本文复制引用
巴凯,倪端,杜若冰,魏雪琴..瑞马唑仑在阻生牙拔除术中的应用[J].华西口腔医学杂志,2024,42(4):476-480,5.基金项目
Henan Province Science and Technology Research Program(232102310491) 河南省科技攻关项目(232102310491) （232102310491）
