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Pretreatment and analysis techniques development of TKIs in biological samples for pharmacokinetic studies and therapeutic drug monitoring

Lan Chen Yuan Zhang Yi-Xin Zhang Wei-Lai Wang De-Mei Sun Peng-Yun Li Xue-Song Feng Yue Tan

药物分析学报(英文)2024,Vol.14Issue(4):439-459,21.
药物分析学报(英文)2024,Vol.14Issue(4):439-459,21.DOI:10.1016/j.jpha.2023.11.006

Pretreatment and analysis techniques development of TKIs in biological samples for pharmacokinetic studies and therapeutic drug monitoring

Pretreatment and analysis techniques development of TKIs in biological samples for pharmacokinetic studies and therapeutic drug monitoring

Lan Chen 1Yuan Zhang 1Yi-Xin Zhang 1Wei-Lai Wang 1De-Mei Sun 1Peng-Yun Li 2Xue-Song Feng 1Yue Tan3

作者信息

  • 1. School of Pharmacy,China Medical University,Shenyang,110122,China
  • 2. Institute of Pharmacology and Toxicology Institution,National Engineering Research Center for Strategic Drugs,Beijing,100850,China
  • 3. Department of Gastroenterology,Shengjing Hospital of China Medical University,Shenyang,110022,China
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摘要

关键词

TKIs/Microextraction technique/HRMS methods/Pharmacokinetic studies/Therapeutic drug monitoring

Key words

TKIs/Microextraction technique/HRMS methods/Pharmacokinetic studies/Therapeutic drug monitoring

引用本文复制引用

Lan Chen,Yuan Zhang,Yi-Xin Zhang,Wei-Lai Wang,De-Mei Sun,Peng-Yun Li,Xue-Song Feng,Yue Tan..Pretreatment and analysis techniques development of TKIs in biological samples for pharmacokinetic studies and therapeutic drug monitoring[J].药物分析学报(英文),2024,14(4):439-459,21.

基金项目

This work was supported by the Natural Science Foundation of Liaoning Province,China(Grant No.:2023-MS-172). (Grant No.:2023-MS-172)

药物分析学报(英文)

2095-1779

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