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急性子宫颈炎的诊断及鉴别诊断OA北大核心CSTPCD

Diagnosi,s and differential diagnosis of acute cer-vicitis

中文摘要英文摘要

子宫颈位于相对"有菌"的下生殖道和相对"无菌"的上生殖道之间,是上生殖道的"门户".急性子宫颈炎较为明确的病原体为性传播病原体,即外源性病原体,包括沙眼衣原体、淋病奈瑟菌、生殖支原体等,但仍有50%的患者致病菌并不明确.阴道与子宫颈位置毗邻,阴道内源性病原体上行可导致子宫颈炎.近年来研究表明,细菌性阴道病相关病原体与子宫颈炎相关.急性子宫颈炎可进一步导致盆腔炎、不孕、早产、流产、新生儿感染等,正确诊断和治疗对预防子宫颈炎远期并发症至关重要.急性子宫颈炎的诊断分为临床诊断和病原学诊断.临床诊断依据特征性体征和子宫颈、阴道分泌物显微镜下白细胞计数.随着病原体分子诊断技术的长足发展,其在子宫颈炎诊断中也表现出越来越重要的作用.文章介绍了急性子宫颈炎的诊断方法,以及各种方法的优点及局限性,并对其需要鉴别的疾病进行讨论.

The cervix is the"gateway"between the relatively"insterile"lower genital tract and the rela-tively"sterile"upper genital tract.The pathogenic bacteria of acute cervicitis mainly are sexually trans-mitted pathogens.Namely,the exogenous pathogens,including Chlamydia trachomatis,Neisseria gonor-rhoeae Mycoplasma genitalium,etc.,but the pathogenic bacteria are still unknown in 50%of patients.The vagina is adjacent to the cervix,and the ascending vaginal endogenous pathogens can lead to cervicitis.Recent studies have shown that the bacterial vaginosis-associated pathogens are asociated with cervicitis.Acute cervicitis can further lead to pelvic inflammatory dis-ease,infertility,premature birth,miscarriage,neonatal infection,etc.,and correct diagnosis and treatment is essential to prevent the long-term sequelae of cervi-citis.The diagnosis of acute cervicitis is divided into clinical and etiological diagnosis.Clinical diagnosis and treatment is based on characteristic signs and microscopic leukocytes of cervical and vaginal dis-charge.With the rapid development of molecular di-agnostic technology and its wide application in clinical practice,their diagnostic performance in pathogens has also shown an increasingly important role.This article describes the diagnostic approach and their advantages and limitations of acute cervicitis,and discusses other disease that need to be differentiated.

董梦婷;薛凤霞

天津医科大学总医院妇产科天津市女性生殖健康与优生重点实验室,天津 300052

临床医学

急性子宫颈炎诊断鉴别诊断核酸扩增方法

acute cervicitisdiagnosisdifferential diagnosisnucleic acid amplification methods

《中国实用妇科与产科杂志》 2024 (007)

676-679 / 4

国家自然科学基金(81471419);天津市重大疾病防治科技重大专项(18ZXDBSY00200)

10.19538/j.fk2024070102

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