半夏泻心汤治疗新型冠状病毒感染后失眠的疗效OA

[Abstrcat]Objective To explore the therapeutic effect of Banxia Xiexin Decoction on insomnia after corona virus disease 2019.Methods A total of 120 patients with insomnia after corona virus disease 2019 admitted to Suzhou Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine from January 2023 to June 2023 were divided into experimental group and control group,with 60 cases in each group.The control group was treated with Esazolam,the experimental group was treated with Banxia Xiexin decoction,both groups were treated for 4 weeks.The clinical efficacy,sleep quality,TCM syndrome score,depression score and 5-hydroxytryptamine(5-HT)level before and after treatment were compared between the two groups.Results The effective rate of experimental group was higher than that of control group(P＜0.05).After treatment,PSQI scores,TCM syndrome scores,17-item Hamilton Depression Scale(HAMD-17)scores of both groups were decreased(P＜0.05),and the test group were lower than the control group(P＜0.05).After treatment,the level of 5-HT in the experimental group was higher han that in the control group(P＜0.05).Conclusion Banxia Xiexin Decoction can improve the therapeutic effect of insomnia after novel coronavirus infection,improve sleep quality,traditional Chinese medicine syndrome,depression,and reduce 5-HT level.