水稻"混血杂交"群体揭示遗传互作奥秘OA北大核心CSTPCD

Revealing the intrinsic relationship between gene interactions and phenotypes is a key issue in life science research.Most phenotypes are controlled by multiple genes in a coordinated manner,exhibiting complex genetic effects such as dominance and epistasis in addition to additive effects.In a recent study,a"hybrid"population of rice containing 18 421 recombinant inbred lines was constructed,successfully identifying 96 high-confidence candidate genes controlling 16 agronomic traits.The study analyzed the epistatic effects among genes,constructed a genetic interaction network consisting of 19 hub genes,revealed potential interactions among genes,and discovered 170"masking"epistatic interac-tions.This research provides important data and material resources for genetic studies in rice,establishes a new para-digm for crop genetics research,greatly accelerates the discovery of genes related to important traits,advances the functional analysis of quantitative trait gene interactions,and provides genetic resources and theoretical support for mole-cular breeding.