基于数据挖掘探讨晋唐时期治疗消渴的用药规律OA

Objective:To explore the prescription and drug composition rules and characteristics of the treatment of diabetes in the representative works of prescriptions and medicines in the Jin and Tang Dynasties,in order to provide theoretical basis and drug reference for the clinical diagnosis and treatment of this disease in traditional Chinese medi-cine.Methods:The prescriptions involved in the electronic version of the fifth edition of"Chinese Medical Classics""Emergency Prescriptions for the Elbow","Xiaopin Prescriptions","Gui Yi Prescriptions of Liu Juanzi","Qianjin Yaofang","Qianjin Yifang",and"Wai Tai Mi Yao"were retrieved and sorted,and data mining technology was used for analysis.Results:119 prescriptions involving 149 drugs were collected,and 20 high-frequency Chinese medicines(frequency≥10%)were licorice,Ophiopogon Japonicus,Trichosanthes Kirilowii,Ginseng,and Rehmannia Glutinosa.There were 39 types of drugs,including Qi-Tonifying drugs,Yin-Tonifying drugs,and heat-clearing and fire-purging drugs.The drug properties were mainly cold,and the taste was mostly sweet and bitter.The main meridians were lung meridian,spleen meridian,and stomach meridian,followed by heart meridian and kidney meridian.Association rule analysis obtained 15 drug combinations;and 3 core drug clusters were mined.Conclusion:The diagnosis and treatment of diabetes by doctors in Jin and Tang dynasties was based on the Neijing,which pioneered the treatment of the three types of diabetes and constructed a common clinical syndrome framework,which opened up a broad road for later doc-tors to study and expand the disease.