北京中医药大学学报2024，Vol.47Issue(8)：1043-1048,6.DOI:10.3969/j.issn.1006-2157.2024.08.002
从"脑气络-病络"理论探析癫痫发作的病机及治疗
Discussion on the pathogenesis and treatment of epilepsy from the theory of "brain's qi collateral-abnormal collateral"
摘要
Abstract
Epilepsy is a disease of the central nervous system caused by excessive neuronal discharges in the brain,characterized by sudden,recurrent and self-limited onset. The brain's qi collateral and the brain neural network are highly correlated and internally consistent in terms of structure and function. The theory of "brain's qi collateral-abnormal collateral",which is centered on the structural disorder and dysfunction of brain's qi collateral leading to the poor circulation of brain's qi collateral,can comprehensively explain the related pathogenesis of epilepsy and the law of disease evolution,so it has important clinical value. Taking the pathogenic characteristics as an entry point and based on the theory of "brain's qi collateral-abnormal collateral",this paper argues that phlegm and qi stagnation,wind in the brain's qi collateral,and phlegm and blood stagnation damaging the brain's collaterals,as well as the structural and functional characteristics of brain's qi collateral that circulate bi-directionally are the key factors for epilepsy to present sudden,recurrent,and self-limited characteristics. According to the therapeutic principle of "Collaterals need to be unobstructed to function normally",it is proposed that the method of regulating the qi and collaterals should be used as the basic treatment principle throughout the treatment. In addition,the method of resolving phlegm and eliminating blood stasis is supplemented for different pathological changes,while combining the syndrome differentiation of zang-fu viscera and attaching importance to the accompanying symptoms of epileptic seizures,to regulate the brain's qi collateral to achieve the effects of wind quenching and epileptic arrest. This is to provide reference for the treatment of epilepsy in traditional Chinese medicine.关键词
癫痫/脑气络/病络/发作特点/病机Key words
epilepsy/brain's qi collateral/abnormal collateral/pathogenic characteristics/pathogenesis分类
医药卫生引用本文复制引用
孙田烨,王凯悦,阎明源,黎莉莉,刘金民..从"脑气络-病络"理论探析癫痫发作的病机及治疗[J].北京中医药大学学报,2024,47(8):1043-1048,6.基金项目
国家自然科学基金项目(No.81774277) （No.81774277）
国家中医药管理局京津冀中医药协同发展项目(No.GZY-GCS-2017-0) （No.GZY-GCS-2017-0）
北京中医药大学基本科研业务费项目(No.2020-tsxk-001) National Natural Science Foundation of China(No.81774277) （No.2020-tsxk-001）
