茶叶科学2024，Vol.44Issue(4)：543-553,11.
表没食子儿茶素没食子酸酯预防并改善非酒精性脂肪性肝病的作用机制及研究进展
The Mechanism and Research Progress of Epigallocatechin Gallate in Improving Non-alcoholic Fatty Liver Disease
摘要
Abstract
The incidence of nonalcoholic fatty liver disease (NAFLD) is increasing year by year and there is no specific drug available. The active ingredient of green tea,epigallocatechin gallate (EGCG),has been widely proven to have a favorable ameliorative effect on NAFLD in the low dose range. Some of the mechanisms by which EGCG delays the development of NAFLD through anti-oxidative stress,anti-inflammation,inhibition of iron death,reduction of lipogenesis,up-regulation of autophagy,modulation of intestinal flora,and reduction of bile acid metabolism were summarized in this paper,so as to provide insights for in-depth research on improving NAFLD.关键词
非酒精性脂肪性肝病/表没食子儿茶素没食子酸酯/氧化应激/炎症Key words
nonalcoholic fatty liver disease/epigallocatechin gallate/oxidative stress/inflammation分类
农业科技引用本文复制引用
陈佳欣,张锦佳,左会灵,焦宇航,石安华..表没食子儿茶素没食子酸酯预防并改善非酒精性脂肪性肝病的作用机制及研究进展[J].茶叶科学,2024,44(4):543-553,11.基金项目
国家自然科学基金(82360863)、云南省科学技术厅中医联合专项-重点项目(202001AZ070001-005) （82360863）
