云南化工2024，Vol.51Issue(8)：6-14,9.DOI:10.3969/j.issn.1004-275X.2024.08.02
近红外Ⅱ区有机荧光探针的构筑与生物成像研究进展
Design of Near-Infrared Ⅱ Organic Fluorescence Probes and Their Progress in Bioimaging
摘要
Abstract
Fluorescence imaging technology is widely used in the fields of biomedicine and disease diagnosis due to its advantages of high sensi-tivity,strong specificity and real-time imaging.Near-infrared Ⅱ region(NIR-Ⅱ,1000-1700 nm)fluorescence imaging technology can ef-fectively overcome the poor tissue penetration,light absorption and autofluorescence interference of biological samples,and low signal-to-noise ratio in the process of visible light(390-780 nm)fluorescence imaging and improve fluorescence imaging sensitivity,resolution and tis-sue penetration of fluorescence imaging.In recent years,organic fluorescent probes have received more and more attention due to their unique advantages such as good biocompatibility,low toxicity and low cost.We systematically introduce the research progress of organic fluorescent probes in the near-infrared Ⅱ region in recent years according to the classification of identification objects and biological imaging applications.Moreover,we also discuss their application in disease diagnosis and fluorescent tracking,laying the foundation for the development of organic fluorescent probes in the near-infrared Ⅱ region.关键词
近红外Ⅱ区/有机小分子探针/荧光探针/生物成像Key words
Near Infrared Ⅱ Region/Organic Small Molecule Probes/Fluorescent Probe/Bioimaging分类
化学引用本文复制引用
王敏娟,王兴凤,包永芬,单士刚,欧莹宝,魏明杰..近红外Ⅱ区有机荧光探针的构筑与生物成像研究进展[J].云南化工,2024,51(8):6-14,9.基金项目
湖北省自然科学基金资助项目(No.2022CFB781) （No.2022CFB781）
湖北科技学院博士启动资助项目(No.170562). （No.170562）
