多糖在短链脂肪酸代谢和慢性病调控中的作用研究进展OACSTPCD
Research Progress of Effect of Polysaccharides in Metabolism of Short Chain Fatty Acids and Regulation of Chronic Diseases
目的:综述肠道菌群通过利用多糖产生代谢产物短链脂肪酸(SCFAs)以及SCFAs对机体的作用,为多糖和SCFAs在营养学上的研究与应用提供科学依据.方法:通过文献查阅,概述多糖对SCFAs的作用,总结SCFAs对机体一些疾病的改善作用.结果:多糖作为碳源被肠道微生物消化利用,通过生成SCFAs在人体健康中发挥重要的生理功能.结论:多糖的消化利用与SCFAs代谢和调控慢性疾病密切相关,期待对多糖在SCFAs代谢和慢性病改善方面的应用研究有正向的指导作用.
[Objective]To review the role of intestinal flora in the production of short chain fatty acids(SCFAs)from polysaccharides and SCFAs on the body,so as to provide reference for the future research and application of polysaccharides and SCFAs in nutrition.[Method]Summarize the effect of polysaccharides on SCFAs and the improvement effect of SCFAs on some diseases through literature review.[Result]Polysaccharides were digested and utilized by intestinal microbes as carbon sources,and played an important physiologi-cal role in human health by generating SCFAs.[Conclusion]The digestion and utilization of polysaccharides are closely related to the metabolism of SCFAs and the regulation of chronic diseases.It is expected to have a positive guiding role in the application of polysac-charides in the metabolism of SCFAs and the improvement of chronic diseases.
张雅施;徐翠菊;张愉;谢真;宗爱珍;刘丽娜;杜方岭;李延琪;徐同成
山东省农业科学院农产品加工与营养研究所/山东省农产品精深加工技术重点实验室/农业农村部新食品资源加工重点实验室/山东省特殊医学用途配方食品工程技术研究中心,济南 250100聊城市茌平区农业农村局,山东聊城 252100
多糖肠道菌群短链脂肪酸作用机制慢性病
polysaccharideintestinal florashort-chain fatty acidsmechanismchronic disease
《中国食物与营养》 2024 (008)
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国家重点研发计划项目(项目编号:2019YFD1002704);山东省农业科学院农业科技创新工程(项目编号:CXGC2022B05);泰山产业领军人才工程专项经费-徐同成(项目编号:2019TSCYCX-35).
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