膳食纤维在调节猪肠道健康与缓解肠道疾病中的作用及其机制OA北大核心CSTPCD

In recent years,dietary fiber(DF)as a non-grain feed resource has become a research hotspot in the development of low-protein feed and it is an important nutritional component of feed for pigs.Numerous studies have confirmed that DF plays multiple roles in regulating pig intestinal health and alleviating intestinal disorders,with its mechanism being highly complex.DF regulates the intestinal microbiota by selecting microbial communities and maintaining an anaerobic environment in the intestine.Simultaneously,it directly stimulates immune cells,upregulates the expression of tight junction proteins,and exerts immune-regulatory effects.Additionally,DF increases the number of intestinal crypts and the viscosity of chyme,and its metabolites provide the primary energy sources for intestinal epithelial cells and symbiotic microorganisms,promote the development and renewal cycle of intestinal crypt cells and epithelial cells,and thus improve the intestinal tissue morphology.The author systematically sorts out and summarizes the relevant research in recent years,and summarizes the definition and classification of DF and its research results in preventing pig intestinal disorders.Starting with the optimizing microbial community structure,improving the mucosal barrier and intestinal morphology,the specific function and potential mechanism of DF in regulating the intestinal health of pigs have been analyzed,and the existing problems and future research focus have been proposed,which provides new perspectives and evidence for further investigating the impact of DF on pig intestinal health,while also laying a theoretical foundation for the development of non-grain feed resources rich in DF and developing grain-saving and sustainable green pig breeding.