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食源性活性物质稳态化及靶向递送载体的研究进展

岳庆 李媛 史文鹏 张春月 李星 刘翔宇 吕鸣春 张辉 袁育 杨志

食品科学2024,Vol.45Issue(19):272-286,15.
食品科学2024,Vol.45Issue(19):272-286,15.DOI:10.7506/spkx1002-6630-20231123-182

食源性活性物质稳态化及靶向递送载体的研究进展

Research Progress on the Stabilization and Targeted Delivery Carriers for Food Bioactive Compounds

岳庆 1李媛 2史文鹏 3张春月 1李星 1刘翔宇 1吕鸣春 4张辉 1袁育 1杨志5

作者信息

  • 1. 中国农业大学食品科学与营养工程学院,食品胶体与营养递送研究中心,北京 100083
  • 2. 中国农业大学食品科学与营养工程学院,食品胶体与营养递送研究中心,北京 100083||深圳市中农大前沿技术研究院,广东深圳 518000
  • 3. 益欣康华生物医药科技有限公司,北京 100083
  • 4. 深圳市中农大前沿技术研究院,广东深圳 518000
  • 5. 梅西大学食品与先进技术学院,新西兰奥克兰 0632
  • 折叠

摘要

Abstract

Food bioactive compounds,such as polyphenols,carotenoids,functional proteins and unsaturated fatty acids,have been used as important ingredients of functional foods due to their diverse biological activities.However,the low aqueous solubility,poor stability and limited bioavailability of these compounds limit their applications in the food industry.The preparation of delivery carriers from natural food macromolecules offers a promising approach to enhance the solubility,stability,and bioavailability of bioactive compounds.As a novel delivery system,intelligent responsive delivery carriers enable precise targeted and controlled release of bioactive compounds,thus improving their bioavailability.In addition,the delivery carriers have the capacity to effectively improve the added nutritional value,enhance the sensory properties,and extend the shelf life of functional foods.This review summarizes the functional properties of food bioactive compounds,the challenges in their application and their steady-state delivery strategies,with a particular emphasis on the common intelligent responsive delivery carriers and their mechanisms of action.Finally,this article discusses the application of these delivery carriers in functional foods,and provides an outlook on future research on bioactive compound delivery systems.

关键词

食源性活性物质/稳态化/递送载体/靶向控释/生物利用率/功能食品

Key words

food bioactive compounds/stabilization/delivery systems/targeted and controlled release/bioavailability/functional foods

分类

轻工纺织

引用本文复制引用

岳庆,李媛,史文鹏,张春月,李星,刘翔宇,吕鸣春,张辉,袁育,杨志..食源性活性物质稳态化及靶向递送载体的研究进展[J].食品科学,2024,45(19):272-286,15.

基金项目

国家自然科学基金面上项目(32172345) (32172345)

食品科学

OA北大核心CSTPCD

1002-6630

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