解剖学杂志2024,Vol.47Issue(4):343-347,5.DOI:10.3969/j.issn.1001-1633.2024.04.012
干细胞移植对缺血性脑卒中的保护作用及机制研究进展
Research progress on the protective effect and mechanism of stem cell transplantation in ischemic stroke
摘要
Abstract
Ischemic stroke is characterized by high mortality and disability rates,and conventional treatment approaches have limited effectiveness in improving outcomes.However,using stem cells has emerged as a promising therapeutic option for ischemic stroke as they can promote angiogenesis,regulate immune responses,inhibit cell apoptosis,reduce oxidative stress,replace damaged cells,and secrete neurotrophic factors.As a result,stem cell therapy has become a research hotspot in the field of ischemic stroke treatment.This article provides an overview of the neuroprotective effects of stem cells in treating ischemic stroke,highlights related research advancements,and aims to support further clinical research and application of stem cell therapy for ischemic stroke.关键词
缺血性脑卒中/干细胞/免疫调节/血管再生/氧化应激Key words
ischemic stroke/stem cells/immunoregulation/angiogenesis/oxidative stress分类
医药卫生引用本文复制引用
孙宇康,段彦哲,贾炜豪,杨蓉,董春波,马存根,翟晓艳,张瑞平..干细胞移植对缺血性脑卒中的保护作用及机制研究进展[J].解剖学杂志,2024,47(4):343-347,5.基金项目
国家中医药管理局项目(2021-KF-02T) (2021-KF-02T)
山西省中医药管理局项目(2023ZYYB046) (2023ZYYB046)
山西省教育厅科技创新项目(2021L360) (2021L360)
山西省科技厅面上项目(202203021221196,202203021221199) (202203021221196,202203021221199)
山西省科技创新人才青年团队项目(202204051001028),山西中医药大学科技创新团队项目(2022TD2010) (202204051001028)
山西省卫健委医学科技领军团队项目(2020TD05) (2020TD05)