支架联合抽吸取栓治疗高龄前循环急性大血管闭塞性脑卒中的疗效OACSTPCD

Objective To investigate the efficacy of stenting combined suction embolization in treating elderly acute large vascular occlusion stroke(ALVOS)in anterior circulation.Methods Sixty ALVOS patients who received stent thrombectomy alone from January 2020 to December 2020(control group)and 60 ALVOS patients who received stenting combined suction embolization from January 2021 to December 2022(observation group)were compared.The clinical data of the two groups before and after treatment were compared and analyzed.Results The total vascularization rate of the observation group was significantly higher than the control group(P＜0.05).The decrease of monocyte chemoattractant protein,IL-6,TNF-α,neuron-specific enolase,central nerve specific protein and NIHSS and mRS scores after treatment in the observation group were more significantly than those in the control group(all P＜0.05).The total effective rate in the observation group was significantly higher than that in the control group(P＜0.05).Conclusion Compared with stent thrombectomy alone,stent combined with thrombectomy can effectively improve the vascular revascularization rate in elderly patients with ALVOS,regulate the expression levels of inflammatory cytokines and neurological function prognosis-related factors,and have a better regulation effect on nerve function recovery and inflammatory response,and improve the prognosis of patients.