新医学2024，Vol.55Issue(9)：677-684,8.DOI:10.3969/j.issn.0253-9802.2024.09.001
减重后为何会出现体重反弹?
Why does weight regain occur after weight loss?
摘要
Abstract
Obesity,as a global health issue,presents significant challenges in its treatment and management,particularly the phenomenon of weight regain.This not only undermines the effectiveness of weight loss efforts but may also have further impacts on the physical and mental health of patients.This article delves into the issue of weight regain during the treatment of obesity,analyzing its definition,prevalence,and health implications.It elucidates the biological mechanisms of weight regain from aspects such as the body weight set-point theory,metabolic adaptation,immune cell phenotypic changes,lipid metabolism,and appetite regulation.A comprehensive management strategy is proposed,including lifestyle adjustments,continuous pharmacological treatment,surgical intervention,and multidisciplinary collaboration,aiming to achieve long-term weight control in obese patients.The study emphasizes the continuity and individualization of weight management,providing scientific guidance for clinical practice.关键词
肥胖/体质量反弹/体质量管理Key words
Obesity/Regain weight/Weight management引用本文复制引用
张群,谭莺,朱延华,陈燕铭..减重后为何会出现体重反弹?[J].新医学,2024,55(9):677-684,8.基金项目
国家自然科学基金(82270886) （82270886）
中山大学临床医学研究5010计划(2023006) （2023006）
