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长新冠综合征研究现状及健康管理应对策略OACSTPCD

Research status of long COVID and health management strategies

中文摘要英文摘要

新型冠状病毒(SARS-CoV-2)仍在世界范围内广泛传播,据统计目前已有超过 7.6 亿新型冠状病毒感染(COVID-19)确诊病例.虽然大多数感染者能获得治愈,但仍有不少患者在感染SARS-CoV-2 后的 2~3 个月甚至更长时间,出现持续的头晕、疲劳、乏力、咳嗽、胸痛等临床症状.国际上将这类不适症状称为长新冠综合征(long COVID,长新冠).长新冠的出现给人们的健康带来新的危机,不仅影响患者的生活质量及工作,也给社会带来巨大的医疗保健压力.探索长新冠带给人们的影响及其发生机制,制定长新冠健康管理策略,以更好地预防、治疗长新冠,仍是世界范围内研究的重点.文章介绍了长新冠的定义,并对其发生机制、常见系统临床表现、危险因素及长新冠健康管理等在近年取得的研究进展进行综述,为临床医师认识长新冠提供更多思路.

The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is still spreading widely around the world,and it is estimated that there are more than 760 million confirmed cases of SARS-CoV-2 infection(COVID-19).Although most of the infected patients can be cured,there are still many patients who experience persistent clinical symptoms such as dizziness,fatigue,weakness,coughing and chest pain,etc.at two to three months or even longer after being infected with SARS-CoV-2.Internationally,this type of discomforts is referred to as long COVID.The emergence of long COVID has brought a new crisis to people's health,which not only affects the quality of life and work of patients,but also brings great pressure on the health care of the society.Continuously exploring the impact of long COVID and its underlying mechanism,developing health management strategies for long COVID,and better prevention and treatment of long COVID are still the focus of research worldwide.The article introduces the definition of long COVID and reviews recent research progress in its underlying mechanism,common systemic clinical manifestations,risk factors,and health management of long COVID,aiming to provide more ideas for deepening clinicians'understanding of long COVID.

吴林;袁晓帆;杨帆;陈红

电子科技大学医学院,四川 成都 610054电子科技大学医学院,四川 成都 610054||四川省医学科学院·四川省人民医院(电子科技大学附属医院)全科医学中心,四川 成都 610072

新型冠状病毒感染长新冠综合征临床表现机制健康管理

COVID-19Long COVIDClinical manifestationsMechanismsHealth management

《新医学》 2024 (009)

729-737 / 9

四川省科技计划项目(2022YFS0264);四川省自然科学基金(24NSFSC2240)

10.3969/j.issn.0253-9802.2024.09.008

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