中国脑血管病杂志2024，Vol.21Issue(9)：632-637,6.DOI:10.3969/j.issn.1672-5921.2024.09.008
放射治疗后颈动脉狭窄的分子机制研究进展
Advances in molecular mechanisms of carotid artery stenosis after radiotherapy
摘要
Abstract
In recent years,radiation therapy has become a cornerstone in the treatment of head and neck tumors,significantly improving patient survival rates.However,the issue of radiation-induced carotid artery stenosis has garnered increasing attention.Characterized by multiple,long-segment,and unstable lesions,radiation-induced carotid stenosis presents unique challenges that traditional therapeutic approaches struggle to address.This review systematically summarized the pathological features and underlying mechanisms of radiation-induced carotid stenosis,with a focus on the roles of endothelial cells,smooth muscle cells,and vasa vasorum damage.Future research directions and preventive strategies are also discussed.关键词
颈动脉狭窄/放射治疗/分子机制/综述Key words
Carotid artery stenosis/Radiotherapy/Molecular mechanism/Review引用本文复制引用
张潇,崔晟岩,徐然,李家耀,焦力群,王韬..放射治疗后颈动脉狭窄的分子机制研究进展[J].中国脑血管病杂志,2024,21(9):632-637,6.基金项目
国家自然科学基金青年科学基金项目(82301468) （82301468）
