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动脉瘤性蛛网膜下腔出血患者颅内压监测及管理的研究进展OA北大核心CSTPCD

Research progress on intracranial pressure monitoring and management in patients with aneurysmal subarachnoid hemorrhage

中文摘要英文摘要

动脉瘤性蛛网膜下腔出血(aSAH)是对脑组织最具损伤性的疾病之一,这种损伤的形成存在多重机制,颅内压升高是其中尤为重要的一个.临床实践研究表明,aSAH患者出现颅内压升高后的一系列病理生理变化,不仅加剧了脑组织的继发性损伤,也成为影响受损脑组织修复的不利因素.既往多项关于颅内压的研究显示,应用颅内压监测并指导治疗可以改善创伤性脑损伤患者的预后,颅内压监测已成为其常规临床监测方法.而针对aSAH患者颅内压的临床研究尚少,对于来自创伤性脑损伤患者的研究结果及经验是否适用于aSAH患者的临床实践尚不明确.作者回顾了已报道的相关临床研究,对aSAH患者的颅内压变化规律、适用范围、干预阈值进行综述.

Aneurysmal subarachnoid hemorrhage(aSAH)is one of the most damaging diseases in the brain.It is caused by multiple mechanisms and increased intracranial pressure is one of the most important.In clinical practice,it has been found that aSAH patients have a series of pathophysiological changes after increased intracranial pressure,which not only aggravates the secondary damage of brain tissue,but also becomes an unfavorable factor for the repair of damaged brain tissue.In many past studies on intracranial pressure,the application of intracranial pressure monitoring to guide the treatment of traumatic brain injury(TBI)patients has improved the prognosis of TBI patients,and intracranial pressure monitoring has become a routine clinical monitoring method.However,there are few clinical studies on intracranial pressure in aSAH patients,and it is not clear whether the research results and experience from TBI patients are applicable to the clinical practice of aSAH patients.The authors reviewed the reported clinical studies,and reviewed the change rule,application range and intervention threshold of intracranial presssure in aSAH patients.

傅晓彤;曲鑫;王宁

100053 北京,首都医科大学宣武医院神经外科

蛛网膜下腔出血颅内压动脉瘤,破裂重症监护病房神经危重症管理综述

Subarachnoid hemorrhageIntracranial pressureIntracranial aneurysm,ruptureIntensive care unitsNeurocritical managementReview

《中国脑血管病杂志》 2024 (009)

638-642 / 5

10.3969/j.issn.1672-5921.2024.09.009

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