膳食纤维摄入量与高血压的关系:基于2015-2016年美国国家健康与营养调查数据库(NHANES)的分析OACSTPCD
The relationship between dietary fiber intake and hypertension:an analysis based on the NHANES data from 2015-2016 in the United States
目的 探讨不同人群膳食纤维摄入量与高血压的关系.方法 采用美国国家健康与营养调查数据库(National Health and Nutrition Examination Survey,NHANES)2015-2016 年的数据,将 24h膳食回顾法收集的饮食数据与美国农业部食品和营养数据库相结合计算膳食纤维摄入量;通过问卷调查和移动中心检测的血压数值定义高血压.采用logistic回归模型分析年龄≥18 岁人群的膳食纤维摄入量与高血压的关系,采用广义相加模型(generalized additive model,GAM)、平滑曲线拟合分析两者间的剂量-反应关系.结果 与低膳食纤维摄入者(膳食纤维摄入量<11.75 g/d)相比,在总人群中,高膳食纤维摄入者(膳食纤维摄入量≥18.85 g/d)高血压的患病风险下降 18%(OR=0.82,95%CI 0.68~0.98).男性人群中,高膳食纤维摄入者高血压的患病风险下降 23%(OR=0.77,95%CI 0.60~0.98);女性人群中,当膳食纤维摄入量>28.05 g/d时,膳食纤维摄入量每增加 1 g/d,高血压的患病风险下降 6%(OR=0.94,95%CI 0.89~0.99).年龄>60 岁人群中,高膳食纤维摄入者高血压的患病风险下降 31%(OR=0.69,95%CI 0.48~0.99);年龄≤45 岁人群中,膳食纤维摄入>34.5 g/d时,膳食纤维摄入量每增加 1 g/d,高血压的患病风险下降 6%(OR=0.94,95%CI 0.88~0.99).结论 高膳食纤维摄入与高血压患病风险下降有关,合理增加膳食纤维摄入有助于降低高血压的发生.
Objective To explore the relationship between dietary fiber intake and hypertension in different populations.Methods Dietary fiber intake was calculated using the data from 2015-2016 National Health and Nutrition Examination Survey(NHANES)database by combining dietary data collected by the 24-hour dietary recall method with the USDA Food and Nutritional Database.Hypertension was defined based on blood pressure values obtained through questionnaires and mobile center measurements.Logistic regression models were used to analyze the relationship between dietary fiber intake and hypertension in individuals aged≥18 years.Generalized additive model(GAM)and smoothed curve fitting were used to analyze the dose-response relationship between them.Results Compared with the low dietary fiber intake(<17.75 g/d)group,in the total population,the prevalence risk of hypertension was 18% lower in the high dietary fiber intake(≥18.85 g/d)group(OR=0.82,95% CI 0.68-0.98).In the male population,the risk of hypertension in the high dietary fiber intake group decreased by 23% (OR=0.77,95% CI 0.60-0.98).In the female population,when dietary fiber intake was>28.05 g/d,the risk of hypertension decreased by 6% (OR=0.94,95% CI 0.89-0.99)for 1 g/d increase in dietary fiber intake.In the population aged>60 years,the risk of hypertension decreased by 31% in the high dietary fiber intake group(OR=0.69,95% CI 0.48-0.99).In the population aged≤45 years,the risk of hypertension decreased by 6% (OR=0.94,95% CI 0.88-0.99)for 1 g/d increase when dietary fiber intake>34.5 g/d.Conclusions High dietary fiber intake is associated with a decreased risk of developing hypertension,and a reasonable increase in dietary fiber intake can help reduce the incidence of hypertension.
李林娟;李佼彦;罗小琴
西安交通大学医学部公共卫生学院,西安 710061||西安市人民医院(西安市第四医院)心电生理中心,西安 710004西安市人民医院(西安市第四医院)心电生理中心,西安 710004西安交通大学医学部公共卫生学院,西安 710061||陕西省疾病预防控制与健康促进重点实验室,西安 710061
临床医学
膳食纤维高血压logistic回归剂量-反应关系
dietary fiberhypertensionlogistic regressiondose-response relationship
《中国临床医学》 2024 (005)
734-741 / 8
国家自然科学基金(81874263).Supported by National Natural Science Foundation of China(81874263).
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