基于络病学说"气络""血络"理论探讨糖尿病周围神经病变OA
Exploring Diabetic Peripheral Neuropathy Based on the"Qi Collateral"and"Blood Collateral"of Theories of Collateral Disease
糖尿病易引发微血管病变,其中糖尿病周围神经病变(DPN)为其常见的并发症之一,严重者可能出现坏疽,甚至截肢,也是致残率较高的一种糖尿病并发症.DPN属"痹证""不仁""痿证""血痹"等范畴,因其病情缠绵难愈,常有瘀血阻络、络脉不通的病理改变,与络病"久、瘀、顽、杂"的病机特点基本相似.针对这一病机,笔者从"气络""血络"理论出发,发现瘀血阻络贯穿于DPN整个病程,并且在疾病的不同阶段所呈现出的症状严重程度亦存在差异,因此应将通络治疗作为DPN治疗的核心,采用"补兼通"的治法,即一方面补气阴,养经络,另一方面活血化瘀,疏通经络.络以通为用,运用"通补为宜"的治疗法则,益气养阴荣养其络、活血化瘀疏通其络.
Diabetes often leads to microvascular complications,with diabetic peripheral neuropathy(DPN)being one of its common complications.Severe cases may result in gangrene or even amputation,making it a condition with a high disability rate.DPN falls into categories such as"bi syndrome,""insensibility,""atrophy syndrome,"and"blood bi,"and due to its chronic and difficult-to-cure nature,it often exhibits pathological changes like blood stasis obstructing collaterals and impaired collateral circulation.These characteristics align closely with the pathogenic features of collateral disease,which include chronicity,stasis,persistence,and complexity.In response to this pathogenesis,the author found from the theoretical perspective of"qi collateral"and"blood collateral"that blood stasis obstructs the meridian throughout the entire course of DPN.The severity of symptoms presented at different stages of this disease also varies.Therefore,unblocking collateral treatment should be regarded as the core of DPN treatment,and the treatment method of"supplementing and unblocking"should be adopted.On the one hand,practitioners should replenish qi and yin,nourishing meridians,and on the other hand,practitioners should promote blood circulation and removes blood stasis,unblocking meridian and collateral.Collateral is useful when it is not blocked,and therefore,unblocking and supplementing collateral should be treatment principle for this disease.Replenishing qi and nourishing yin can nourish collateral and activating blood and resolving stasis can unblock collateral.
张慧;张玉福;任秋月;韩景辉;冯志海
河南中医药大学第一附属医院,河南 郑州 450000
气络血络糖尿病周围神经病变
Qi collateralBlood collateralDiabetic peripheral neuropathy
《中医药信息》 2024 (010)
14-18 / 5
国家自然科学基金青年基金项目(82305019)
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