食品科学2025，Vol.46Issue(2)：118-125,8.DOI:10.7506/spkx1002-6630-20240621-148
全谷物及杂豆添加量在小鼠与人体间剂量换算分析
Dietary Dose Conversion of Whole Grains and Non-soy Legumes between Mice and Humans
摘要
Abstract
Moderate intake of whole grains and non-soy legumes can improve glucose and lipid metabolism,but excessive intake may have an adverse effect.Due to the lack of corresponding conversion relationships,the intake of whole grains and non-soy legumes in mouse feed cannot directly serve as a reference for human intake.This paper introduces the addition levels of common whole grains and non-soy legumes in mouse feed and explores their relationship with the recommended dietary intakes(RDI)of common whole grains and non-soy legumes in humans using various methods,including equivalent coefficient,surface area ratio,body shape coefficient,food density,body surface area index,energy conversion,and nutrient conversion methods.The results indicate that the RDI of 50-150 g of whole grains and non-soy legumes in humans could be equivalently converted into addition of 5%-50%whole grains and beans in the feed of mice with a 3 g daily feed intake.Dietary addition of whole grains and non-soy legumes exceeding 50%might place mice at risk for overconsumption.This study provides an important reference for establishing the conversion relationship between the amounts of whole grains and non-soy legumes added to mouse feed and the RDI of whole grains and non-soy legumes in humans.关键词
剂量换算/全谷物/杂豆/体表面积Key words
dose conversion/whole grains/non-soy legumes/body surface area分类
轻工纺织引用本文复制引用
支莉,朱益清,赵亮星,陈睿,赵卿宇,王超,薛勇,沈群..全谷物及杂豆添加量在小鼠与人体间剂量换算分析[J].食品科学,2025,46(2):118-125,8.基金项目
"十四五"国家重点研发计划重点专项(2022YFF1100505) （2022YFF1100505）
