CT理论与应用研究2025，Vol.34Issue(1)：9-16,8.DOI:10.15953/j.ctta.2024.185
mDixon序列与3D全心TFE序列使用SPIR压脂技术3.0T非对比增强冠状动脉磁共振成像诊断性能对比研究
Non-contrast-enhanced 3.0T Whole-heart Coronary MRA:Comparison of Diagnostic Performance between mDixon and WHCA TFE Sequence Using SPIR in CAD Using Coronary Angiography as Reference
摘要
Abstract
Objective:To compare the diagnostic performance between mDixon sequence and WHCA TFE sequence using SPIR for non-contrast-enhanced coronary MRA in patients with suspected coronary artery disease(CAD).Method:This prospective study recruited 45 patients who were scheduled for X-ray coronary angiography(CAG)with suspected CAD in Yantai Yuhuangding hospital.Patients underwent both 3.0T WHCA TFE using SPIR and mDixon coronary MRA examinations before undergoing CAG.Two radiologists independently assessed coronary arteries in terms of subjective image quality(on a scale of 1～5,with 5 denoting the highest image quality),vessel length,vessel diameter,and presence of significant stenoses.CAG was used as the reference standard for detecting the presence of stenoses.Vessel length and diameter were compared between sequences using paired t-tests.Subjective image quality scores were compared between sequences using Wilcoxon tests.Sensitivity,specificity,and accuracy were compared between sequences using McNemar tests.Positive and negative predictive values were compared between sequences using the joint hypotheses test.Results:Two CMRA examinations were successfully performed in 40(88.9%)of 45 patients for analysis.The objective image quality of 3.0T mDixon assessed by both radiologists was(3.9±0.9),and the 3.0T WHCA TFE using SPIR was(3.7±0.9).The mDixon sequence exhibited higher sensitivity,specificity,accuracy,positive predictive value,and negative predictive value in per-segment analysis(78.5%vs.66.1%,96.5%vs.93.8%,91.7%vs.86.6%,88.6%vs.78.9%,and 93.4%vs.88.7%)and higher sensitivity and accuracy in per-vessel analysis(89.4%vs.81.6%and 89.1%vs.83.3%).Conclusion:In comparison with 3.0T WHCA TFE sequence using SPIR,mDixon demonstrated superior diagnostic performance.关键词
冠状动脉磁共振成像/冠状动脉狭窄/诊断性能Key words
coronary angiography magnetic resonance/coronary artery stenoses/diagnostic performance分类
医药卫生引用本文复制引用
王桦滢,陈杨,黄鹏,李跃,张刚,张忠胜,纪海霞,郭浩,马恒..mDixon序列与3D全心TFE序列使用SPIR压脂技术3.0T非对比增强冠状动脉磁共振成像诊断性能对比研究[J].CT理论与应用研究,2025,34(1):9-16,8.基金项目
山东省自然科学基金(应用定量磁共振评估溴隐亭对帕金森病心血管保护作用研究(ZR2022MH274)) （应用定量磁共振评估溴隐亭对帕金森病心血管保护作用研究(ZR2022MH274）
泰山学者(MR心肌灌注成像关键技术创新与应用(tsqn202103197)). （MR心肌灌注成像关键技术创新与应用(tsqn202103197）
